Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), 7089 Trondheim, Norway.
Children's Clinic, St. Olavs Hospital, Trondheim University Hospital, 7006 Trondheim, Norway.
Nutrients. 2018 Nov 20;10(11):1811. doi: 10.3390/nu10111811.
Gestational diabetes mellitus (GDM) is associated with maternal diet, however, findings are inconsistent. The aims of the present study were to assess whether intakes of foods and beverages during pregnancy differed between women who developed GDM and non-GDM women, and to compare dietary intakes with dietary recommendations of pregnancy. This is a nested case-control study within a randomized controlled trial. Women with complete measurements of a 75 g oral glucose tolerance test (OGTT) at 18⁻22 and 32⁻36 weeks gestation were included in the cohort ( = 702). Women were diagnosed for GDM according to the simplified International Association of Diabetes and Pregnancy Study Group criteria at 32⁻36 weeks (GDM women: = 40; non-GDM women: = 662). Dietary data (food frequency questionnaire) was collected at both time points and compared between GDM and non-GDM women. Variability in OGTT values was assessed in a general linear model. Marginal differences between GDM and non-GDM women in intakes of food groups were found. No associations were found between dietary variables and OGTT values. Not all dietary recommendations were followed in the cohort, with frequently reported alcohol consumption giving largest cause for concern. This study did not find dietary differences that could help explain why 40 women developed GDM.
妊娠期糖尿病(GDM)与孕妇的饮食有关,但研究结果并不一致。本研究旨在评估在妊娠期间,患有 GDM 的女性与非 GDM 女性的食物和饮料摄入量是否存在差异,并将其与妊娠期间的饮食建议进行比较。这是一项在随机对照试验中嵌套的病例对照研究。在 18-22 周和 32-36 周的妊娠期间,进行了 75g 口服葡萄糖耐量试验(OGTT)完整测量的女性被纳入队列(n=702)。根据简化的国际妊娠糖尿病协会研究组标准,在 32-36 周时诊断为 GDM(GDM 女性:n=40;非 GDM 女性:n=662)。在两个时间点收集了饮食数据(食物频率问卷),并在 GDM 和非 GDM 女性之间进行了比较。在一般线性模型中评估了 OGTT 值的变异性。发现 GDM 和非 GDM 女性在食物组摄入量方面存在边际差异。饮食变量与 OGTT 值之间没有发现关联。该队列中并非所有的饮食建议都得到了遵循,其中经常报告的饮酒量令人尤为担忧。本研究没有发现可以解释为什么有 40 名女性患有 GDM 的饮食差异。