School of Public Health, Curtin University, Perth, WA, Australia.
Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen, Vietnam.
Nutr J. 2018 Nov 20;17(1):107. doi: 10.1186/s12937-018-0413-3.
Previous research has demonstrated the association between maternal dietary patterns and gestational diabetes (GDM), but evidence in Asian populations remains limited and inconsistent. This study investigated the association between dietary patterns during early pregnancy and the risk of GDM among pregnant women in Western China.
A prospective cohort study was conducted among 1337 pregnant women in Western China. Dietary intakes were assessed at 15-20 weeks of gestation using a validated food frequency questionnaire. GDM was diagnosed by oral glucose tolerance tests at 24-28 weeks of gestation. Exploratory factor analysis was performed to derive dietary patterns, and logistic regression models were used to examine the association between dietary patterns and GDM.
A total of 199 women (14.9%) developed GDM. Three dietary patterns were identified, namely, a plant-based pattern, a meat-based pattern and a high protein-low starch pattern. Notwithstanding a lack of association between dietary patterns and GDM risk in the whole cohort, there was a significant reduction in GDM risk among overweight women (BMI ≥24 kg/m); the odds ratio being 0.29 (95% confidence interval 0.09 to 0.94) when comparing the highest versus the lowest score of the high protein-low starch pattern.
There was no significant association between early pregnancy dietary patterns and GDM risk later in pregnancy for women in Western China, but high protein-low starch diet was associated with lower risk for GDM among women who were overweight at pre-pregnancy.
既往研究表明孕妇的饮食模式与妊娠期糖尿病(GDM)之间存在关联,但亚洲人群的证据仍然有限且不一致。本研究旨在探讨中国西部地区孕妇妊娠早期饮食模式与 GDM 风险之间的关系。
采用前瞻性队列研究,纳入中国西部地区 1337 名孕妇。于妊娠 15-20 周时采用经过验证的食物频率问卷评估膳食摄入量。于妊娠 24-28 周时通过口服葡萄糖耐量试验诊断 GDM。采用探索性因子分析得出饮食模式,采用 logistic 回归模型分析饮食模式与 GDM 之间的关系。
共 199 名孕妇(14.9%)发生 GDM。确定了 3 种饮食模式,分别为植物性饮食模式、动物性饮食模式和高蛋白-低淀粉饮食模式。尽管在整个队列中,饮食模式与 GDM 风险之间无显著关联,但在超重的孕妇(BMI≥24kg/m²)中,高蛋白-低淀粉饮食模式的最高评分与最低评分组之间的 GDM 风险比为 0.29(95%置信区间 0.09 至 0.94),风险显著降低。
对于中国西部地区的孕妇,妊娠早期的饮食模式与妊娠晚期 GDM 风险之间无显著关联,但对于妊娠前超重的孕妇,高蛋白-低淀粉饮食与 GDM 风险降低相关。