Pugachev K K, Kalashnikov V V, Kurika A V, Pavlenko A F, Belous T A
Biull Eksp Biol Med. 1988 Aug;106(8):209-11.
58 human tumors have been studied immunohistologically with the aid of CEA-specific precipitin--crustacin (Cr). The results were in general similar to those which were achieved with anti-CEA-antibodies. But there were some differences. The reaction with Cr in the cytoplasm was mostly diffuse, while the reaction with Ab was localized usually in the peripheral parts of the cytoplasm. The reaction with Cr has a more restricted character and is more expressed in ovarian tumors and less expressed in gastric and colonic tumors than the reaction with Ab.
借助癌胚抗原特异性沉淀素——甲壳素（Cr），对58例人类肿瘤进行了免疫组织学研究。结果总体上与使用抗癌胚抗原抗体所获得的结果相似。但也存在一些差异。在细胞质中与Cr的反应大多呈弥漫性，而与抗体的反应通常定位在细胞质的周边部分。与Cr的反应具有更局限的特征，在卵巢肿瘤中比与抗体的反应表达更明显，而在胃和结肠肿瘤中表达较少。
