Kemin Industries, Inc., Des Moines, IA 50317, USA.
Southern Poultry Research Group, Inc., Watkinsville, GA 30677, USA.
Poult Sci. 2019 Apr 1;98(4):1643-1647. doi: 10.3382/ps/pey523.
This 42-day study evaluated the effects of dietary supplementation with β-1,3-glucan (Aleta™) on the vaccination response to Newcastle disease virus (NDV), avian infectious bronchitis virus (IBV), and infectious bursal disease (IBD) in a non-challenged environment. This trial included 600 chicks (all vaccinated with IBD at the hatchery) which were assigned to 1 of 3 treatments: vaccination (NDV, IBV), no vaccination, or vaccination combined with feed supplemented with Aleta (100 g/MT of feed). The vaccination with Aleta treatment group showed a trend for improved FCR that was not statistically significant. Control birds that were not vaccinated for IBV had significantly lower IBV titers on day 21 compared to birds that were vaccinated (both with and without Aleta). Surprisingly, there was significant separation among treatment groups for NDV titer levels, especially on day 21, where birds vaccinated and supplemented with Aleta had significantly higher titer levels compared to vaccination alone or no vaccination at all. Critically, only 14% of the birds receiving the vaccine plus Aleta had titer levels below the critical titer threshold for immunity compared to 28% of the birds receiving the vaccine alone and 40% of the unvaccinated birds. This suggests that Aleta supplementation may help to improve the vaccination response by birds, especially for NDV.
本为期 42 天的研究评估了在非挑战环境下，β-1,3-葡聚糖（Aleta™）的饮食补充对新城疫病毒（NDV）、禽传染性支气管炎病毒（IBV）和传染性法氏囊病（IBD）疫苗接种反应的影响。该试验包括 600 只小鸡（全部在孵化场接种 IBD 疫苗），它们被分配到 3 种处理方式中的 1 种：接种疫苗（NDV、IBV）、不接种疫苗或接种疫苗并添加 Aleta（饲料中添加 100 g/MT）。添加 Aleta 的接种疫苗处理组显示出改善 FCR 的趋势，但无统计学意义。未接种 IBV 的对照鸡在第 21 天的 IBV 滴度明显低于接种疫苗的鸡（接种 Aleta 与否）。令人惊讶的是，NDV 滴度水平在处理组之间有明显的分离，尤其是在第 21 天，接种疫苗并添加 Aleta 的鸡的滴度水平明显高于单独接种疫苗或完全不接种疫苗的鸡。至关重要的是，与单独接种疫苗的鸡（28%）和未接种疫苗的鸡（40%）相比，只有 14%的接种疫苗加 Aleta 的鸡的滴度水平低于免疫临界滴度阈值，而这一比例在单独接种疫苗的鸡中为 28%，在未接种疫苗的鸡中为 40%。这表明 Aleta 补充剂可能有助于改善鸡的疫苗接种反应，尤其是对 NDV。
