Schwartz C L, Cohen H J
Department of Pediatrics, University of Rochester Medical Center, New York.
Pediatr Clin North Am. 1988 Aug;35(4):853-71. doi: 10.1016/s0031-3955(16)36513-0.
The myelodysplastic and myeloproliferative syndromes are syndromes in childhood that may precede leukemia. Clinical and biologic features are reviewed in this article. Although rare, they offer an unique opportunity to observe the evolution of leukemia and give clues that are helping us to understand the leukemogenic process.
骨髓增生异常综合征和骨髓增殖性综合征是儿童时期可能先于白血病出现的综合征。本文对其临床和生物学特征进行了综述。尽管罕见,但它们提供了一个观察白血病演变的独特机会,并给出了有助于我们理解白血病发生过程的线索。