Suppr超能文献

骨水泥增强经皮椎弓根螺钉在多灶性肿瘤性脊柱骨折治疗中的应用

Use of Cement-Augmented Percutaneous Pedicular Screws in the Management of Multifocal Tumoral Spinal Fractures.

作者信息

Afathi Mehdi, Mansouri Nacer, Farah Kaissar, Benichoux Victor, Blondel Benjamin, Fuentes Stéphane

机构信息

Neurochirurgie C-Chirurgie du Rachis, Hopital Neurologique et Neurochirurgical Pierre Wertheimer, Hospices Civiles de Lyon, Bron, France.

Unité Rachis, Hopital de La Timone, Assistance Publique des Hopitaux de Marseille, Marseille, France.

出版信息

Asian Spine J. 2019 Apr;13(2):305-312. doi: 10.31616/asj.2018.0129. Epub 2018 Nov 29.

Abstract

STUDY DESIGN

Retrospective case series observational study.

PURPOSE

Cancer patients are often aged and are further weakened by their illness and treatments. Our goal was to evaluate the efficiency and safety of using minimally invasive techniques to operate on spinal fractures in these patients.

OVERVIEW OF LITERATURE

Vertebroplasty is now considered to be a safe technique that allows a significant reduction of the pain induced by a spinal tumoral fracture. However, few papers describe the kyphosis reduction that can be achieved by combining percutaneous fixation and anterior vertebral reconstruction.

METHODS

We studied 35 patients seen between December 2013 and October 2016 who had at least one pathological spinal fracture and multiple vertebral metastases. The population's mean age was 67 years, and no patients included had preoperative neurological deficits. The patients underwent a minimally invasive surgery consisting of a percutaneous pedicular fixation with cement-enhanced screws and anterior reconstruction comprising kyphoplasty when possible or corpectomy in cases of excessive damage to the vertebral body. Back pain, traumatic local and regional kyphosis, and Beck's Index were collected pre- and postoperatively, and at 3-, 6-, and 12-month follow-ups.

RESULTS

Mean follow-up time was 13.4 months. Significant reductions in back pain (p<0.001) and local (p<0.001) and regional kyphosis (p=0.006) were found at the 6-month follow-up (alpha risk level <0.05). Beck's Index was also significantly increased, indicating good restoration of the anterior vertebral height. By the final follow-up, no screws had fallen/pulled out. There were no infectious or neurological complications.

CONCLUSIONS

Percutaneous cement-enhanced fixation for pathological fractures has proven a safe and efficient technique in our experience, enabling weak patients to rapidly become ambulatory again without complications. Further follow-up of the patients is necessary to assess the long-term effects of this technique and the continued quality of life of our patients.

摘要

研究设计

回顾性病例系列观察性研究。

目的

癌症患者往往年事已高,疾病和治疗会使他们更加虚弱。我们的目标是评估在这些患者中使用微创技术治疗脊柱骨折的有效性和安全性。

文献综述

椎体成形术现在被认为是一种安全的技术,可显著减轻脊柱肿瘤性骨折引起的疼痛。然而,很少有论文描述通过经皮固定和前路椎体重建相结合可实现的后凸畸形矫正。

方法

我们研究了2013年12月至2016年10月期间就诊的35例患者,这些患者至少有一处病理性脊柱骨折和多处椎体转移。患者的平均年龄为67岁,纳入的患者术前均无神经功能缺损。患者接受了微创手术,包括经皮椎弓根螺钉固定并使用骨水泥强化螺钉,以及前路重建,尽可能进行椎体后凸成形术,对于椎体损伤严重的病例则进行椎体切除。在术前、术后以及3个月、6个月和12个月的随访时收集背痛、创伤性局部和区域性后凸畸形以及贝克指数。

结果

平均随访时间为13.4个月。在6个月随访时发现背痛(p<0.001)、局部后凸畸形(p<0.001)和区域性后凸畸形(p=0.006)均有显著降低(α风险水平<0.05)。贝克指数也显著增加,表明椎体前缘高度得到良好恢复。到最后一次随访时,没有螺钉松动/拔出。没有感染或神经并发症。

结论

根据我们的经验,经皮骨水泥强化固定治疗病理性骨折已被证明是一种安全有效的技术,能使虚弱患者迅速恢复活动能力且无并发症。有必要对患者进行进一步随访,以评估该技术的长期效果以及患者的持续生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecd3/6454290/66c25f17d28c/asj-2018-0129f1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验