Yoshii Fumihito, Tomori Yuichi, Mori Teruo
Department of Neurology, Saiseikai Shonan Hiratsuka Hospital, Hiratsuka, Japan.
Department of Radiology, Saiseikai Shonan Hiratsuka Hospital, Hiratsuka, Japan.
Case Rep Neurol. 2018 Oct 17;10(3):297-301. doi: 10.1159/000493911. eCollection 2018 Sep-Dec.
We present diffusion tensor tractography (DTT) findings in a case of hypertrophic olivary degeneration (HOD) and cerebellar ataxia. A 56-year-old man presented with abnormal ataxic gait and dysarthria. MRI 5 months after onset showed chronic pontine hematoma and enlarged bilateral inferior olivary nuclei. DTT showed decreased volume of the bilateral central tegmental tract, in accordance with the conventional hypothesis that HOD is associated with neurologic insult to the Guillain-Mollaret triangle. The patient's cerebellar ataxia was speculated to be due to decreased decussating fibers of the superior cerebellar peduncle, and this was confirmed by DTT.
我们展示了一例肥厚性橄榄体变性(HOD)伴小脑共济失调患者的扩散张量纤维束成像(DTT)结果。一名56岁男性出现异常共济失调步态和构音障碍。发病5个月后的MRI显示慢性脑桥血肿和双侧下橄榄核增大。DTT显示双侧中央被盖束体积减小,这与HOD与Guillain-Mollaret三角神经损伤相关的传统假说一致。推测患者的小脑共济失调是由于小脑上脚交叉纤维减少所致,DTT证实了这一点。