香料标记物斑贴试验的阳性结果：巴西一家皮肤科中心15年的分析
Positive results of patch tests with fragrance markers: analysis of a 15-year period at a Brazilian dermatology center.
作者信息
Hafner Mariana de Figueiredo Silva, Munhoz Sandy Daniele Germano, Jeldes Ariel Garcia, Lazzarini Rosana
机构信息
Dermatology Clinic, Santa Casa de São Paulo, São Paulo (SP), Brazil.
Medical student, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo (SP), Brazil.
出版信息
An Bras Dermatol. 2018 Nov/Dec;93(6):910-912. doi: 10.1590/abd1806-4841.20187743.
Fragrances may cause allergic contact dermatitis. Data on patients who were patch tested, between 2000 and 2015, with fragrance allergens included in the Brazilian baseline series (balsam of Peru, colophony and fragrance mix I), were collected and analyzed. Of these patients, 258 (13.8%) were positive for fragrance markers, 9.8% being positive for fragrance mix I. Among these 258 there was a predominance of women in their 40s, with hand eczema. The frequency of sensitization to fragrances, as well as the epidemiological profile, was supported by the literature. Fragrance mix I was the main marker. It is important to expand the fragrance markers used in the Brazilian baseline series of patch tests.
香料可能会引起过敏性接触性皮炎。收集并分析了2000年至2015年间对巴西基线系列（秘鲁香脂、松香和香料混合物I）中所含香料过敏原进行斑贴试验的患者数据。在这些患者中，258人（13.8%）香料标记呈阳性，9.8%对香料混合物I呈阳性。在这258人中，40多岁患手部湿疹的女性占多数。香料致敏的频率以及流行病学特征得到了文献的支持。香料混合物I是主要标记。扩大巴西斑贴试验基线系列中使用的香料标记很重要。
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