Bréchet Lucie, Grivaz Petr, Gauthier Baptiste, Blanke Olaf
Laboratory of Cognitive Neuroscience, Brain Mind Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Geneva, Switzerland.
Center for Neuroprosthetics, Swiss Federal Institute of Technology (EPFL), Campus Biotech, Geneva, Switzerland.
Front Behav Neurosci. 2018 Nov 14;12:270. doi: 10.3389/fnbeh.2018.00270. eCollection 2018.
Parietal cortex and adjacent parts of the temporal cortex have recently been associated with bodily self-consciousness (BSC). Similarly, growing evidence suggests that the lateral parietal cortex is crucial for the subjective aspects of episodic autobiographical memory (EAM), which is based on the conscious experience of reliving past events. However, the neuroanatomical relationship between both fundamental aspects remains currently unexplored. Moreover, despite the wealth of neuroimaging data on EAM, only few neuroimaging studies have examined BSC and even fewer examined those aspects of BSC that are most closely related to EAM. Here, we investigated whether regions in the inferior parietal lobule (IPL) that have been involved in spatial aspects of BSC (self-location and first-person perspective), as described by Ionta et al. (2011) are also active in studies investigating autobiographical memory. To examine this relation, we thus compared the regions indicated in the study by Ionta et al. (2011) based on data in healthy participants and neurological patients, with the results from a meta-analytical study we performed based on functional neuroimaging studies on EAM and semantic autobiographical memory (SAM). We report an anatomical overlap bilaterally in the angular gyrus (AG), but not in other parietal or temporal lobe structures between BSC and EAM. Moreover, there was no overlap between BSC and SAM. These preliminary data suggest that the bilateral AG may be a key structure for the conscious re-experiencing of past life episodes (EAM) and the conscious on-line experience of being located and experiencing the world in first-person (BSC).
顶叶皮层以及颞叶皮层的相邻部分最近被认为与身体自我意识（BSC）有关。同样，越来越多的证据表明，外侧顶叶皮层对于情景性自传体记忆（EAM）的主观方面至关重要，而情景性自传体记忆基于对过去事件的有意识重温体验。然而，这两个基本方面之间的神经解剖学关系目前仍未被探索。此外，尽管有大量关于EAM的神经影像数据，但只有少数神经影像研究考察了BSC，甚至更少的研究考察了与EAM最密切相关的BSC方面。在这里，我们研究了如约恩塔等人（2011年）所描述的，参与BSC空间方面（自我定位和第一人称视角）的顶下小叶（IPL）区域，在自传体记忆研究中是否也会活跃。为了检验这种关系，我们基于健康参与者和神经疾病患者的数据，比较了约恩塔等人（2011年）研究中指出的区域，与我们基于对EAM和语义自传体记忆（SAM）的功能神经影像研究进行的一项元分析研究的结果。我们报告了在角回（AG）双侧存在解剖学重叠，但在BSC和EAM之间的其他顶叶或颞叶结构中没有重叠。此外，BSC和SAM之间也没有重叠。这些初步数据表明，双侧AG可能是对过去生活事件进行有意识的重新体验（EAM）以及对以第一人称定位并体验世界的有意识在线体验（BSC）的关键结构。
