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Effect of Excess Iodine Intake from Iodized Salt and/or Groundwater Iodine on Thyroid Function in Nonpregnant and Pregnant Women, Infants, and Children: A Multicenter Study in East Africa.高碘盐和/或地下水碘摄入对非妊娠和妊娠妇女、婴幼儿甲状腺功能的影响:东非的一项多中心研究。
Thyroid. 2018 Sep;28(9):1198-1210. doi: 10.1089/thy.2018.0234. Epub 2018 Aug 22.
2
Effect of excess iodine intake on thyroid diseases in different populations: A systematic review and meta-analyses including observational studies.不同人群中碘摄入过量对甲状腺疾病的影响:一项包括观察性研究的系统评价和荟萃分析
PLoS One. 2017 Mar 10;12(3):e0173722. doi: 10.1371/journal.pone.0173722. eCollection 2017.
3
More than two-thirds of dietary iodine in children in northern Ghana is obtained from bouillon cubes containing iodized salt.加纳北部儿童膳食碘的三分之二以上来自含有碘盐的汤块。
Public Health Nutr. 2017 Apr;20(6):1107-1113. doi: 10.1017/S1368980016003098. Epub 2016 Dec 1.
4
Assessment of iodine status among pregnant women in a rural community in ghana - a cross sectional study.加纳一个农村社区孕妇碘营养状况评估——一项横断面研究
Arch Public Health. 2016 Feb 22;74:8. doi: 10.1186/s13690-016-0119-y. eCollection 2016.
5
Development of thyroid dysfunction among women with excessive iodine intake--A 3-year follow-up.碘摄入过量女性甲状腺功能障碍的发生情况——一项为期3年的随访研究
J Trace Elem Med Biol. 2015;31:61-6. doi: 10.1016/j.jtemb.2015.03.004. Epub 2015 Mar 30.
6
Prevalence of thyroid dysfunction with adequate and excessive iodine intake in Hebei Province, People's Republic of China.中华人民共和国河北省碘摄入充足及过量情况下的甲状腺功能障碍患病率
Public Health Nutr. 2015 Jun;18(9):1692-7. doi: 10.1017/S1368980014002237. Epub 2014 Nov 6.
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Assessment of spatial variation in drinking water iodine and its implications for dietary intake: a new conceptual model for Denmark.评估饮用水碘的空间变异及其对膳食摄入的影响:丹麦的新概念模型。
Sci Total Environ. 2014 Sep 15;493:432-44. doi: 10.1016/j.scitotenv.2014.06.008. Epub 2014 Jun 21.
8
Iodine intake in Somalia is excessive and associated with the source of household drinking water.索马里的碘摄入量过高,与家庭饮用水源有关。
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9
Consequences of excess iodine.碘过量的后果。
Nat Rev Endocrinol. 2014 Mar;10(3):136-42. doi: 10.1038/nrendo.2013.251. Epub 2013 Dec 17.
10
Pathology and the surgical management of goitre in an endemic area initiating supplementary iodine nutrition.在开始补充碘营养的地方性甲状腺肿流行地区,甲状腺肿的病理学及外科治疗
West Afr J Med. 2013 Jan-Mar;32(1):45-51.

加纳碘摄入过量的风险:当前形势、挑战及对未来的教训。

Risks of excess iodine intake in Ghana: current situation, challenges, and lessons for the future.

机构信息

Rochester Institute of Technology, College of Health Sciences and Technology, Wegmans School of Health and Nutrition, Rochester, New York.

Department of Nutritional Sciences, Texas Tech University, College of Human Sciences, Lubbock, Texas.

出版信息

Ann N Y Acad Sci. 2019 Jun;1446(1):117-138. doi: 10.1111/nyas.13988. Epub 2018 Nov 29.

DOI:10.1111/nyas.13988
PMID:30489642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6618322/
Abstract

In Ghana, iodine deficiency was first reported in 1994 among 33% of the population. A nationwide Universal Salt Iodization (USI) program plus other complementary interventions were subsequently implemented as a response. Our paper reviews the current risks of excess iodine status in Ghana and identifies policy and research gaps. A mixed methods review of 12 policies and institutional reports and 13 peer-reviewed articles was complemented with consultations with 23 key informants (salt producers and distributors, food processors, regulatory agency officials, and healthcare providers) purposively sampled between May and August 2017. The findings show a strong policy environment indicated by regulations on food and salt fortification (Act 851), including the USI regulation. However, currently, only a third of Ghanaian households use adequately iodized salt. Recent evidence shows that voluntarily fortified processed foods (including condiments) supply a considerable amount of iodine to the food system. Limited biological impact data suggest possible household exposure to excessive dietary iodine (>15 parts per million). Currently, there is no systematic tracking of iodine content from fortified foods and other sources. Cross-sectoral actions are needed to understand this situation better. Key research gap is the lack of comprehensive data on iodine content and intake from other sources in Ghana.

摘要

在加纳,1994 年首次报告了 33%的人群存在碘缺乏症。随后,作为应对措施,加纳实施了全国范围内的普遍食盐碘化 (USI) 计划和其他补充措施。我们的论文回顾了加纳目前碘过量的风险,并确定了政策和研究方面的差距。通过对 12 项政策和机构报告以及 13 篇同行评议文章进行混合方法综述,并于 2017 年 5 月至 8 月期间与 23 名关键信息提供者(盐生产商和分销商、食品加工商、监管机构官员和医疗保健提供者)进行了咨询,对当前的情况进行了审查。调查结果表明,法规(第 851 号法案)涵盖了食品和盐强化的相关规定,为加纳营造了强有力的政策环境,其中包括 USI 法规。然而,目前只有三分之一的加纳家庭使用足够的碘化盐。最近的证据表明,自愿强化加工食品(包括调味料)为食品系统提供了相当数量的碘。有限的生物影响数据表明,家庭可能会接触到过量的膳食碘(>15 微克/毫升)。目前,没有系统地跟踪强化食品和其他来源的碘含量。需要采取跨部门行动来更好地了解这种情况。一个关键的研究差距是加纳缺乏关于其他来源的碘含量和摄入量的综合数据。