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后路病椎固定法在胸段脊柱结核前后路联合手术中的临床疗效

Clinical Effectiveness of the Posterior Affected-Vertebrae Fixation Method in Posterior-Anterior Surgery to Treat Thoracic Spinal Tuberculosis.

作者信息

Liang Qiang, Wang Qian, Long Guo, Ma Wenxin, Jin Weidong, Liu Liehua, Wu Yuexiang, Shi Jiandang, Wang Zili

机构信息

Department of Spinal Surgery, General Hospital of Ningxia Medical University, Yinchuan, China.

Hillsborough Community College, Tampa, Florida, USA.

出版信息

World Neurosurg. 2019 Mar;123:29-39. doi: 10.1016/j.wneu.2018.11.199. Epub 2018 Nov 29.

Abstract

OBJECTIVE

The present retrospective comparative analysis was conducted to assess the effectiveness of affected-vertebrae fixation versus short-segment fixation to treat thoracic spinal tuberculosis.

METHODS

The present study included 110 patients receiving treatment for thoracic spinal tuberculosis at our hospital from January 2006 to June 2013. All cases involved the use of posterior spinal correction, posterior lateral fusion, internal fixation, anterior decompression, radical debridement, and intervertebral supporting bone grafts. The cases were divided by the scope of posterior internal fixation into the affected-vertebrae fixation group (n = 62) and the short-segment fixation group (n = 48). Statistical analysis was used to compare the clinical effectiveness, laboratory test results, and imaging findings.

RESULTS

The mean surgical blood loss, mean operating time, and mean inpatient expenditures were all significantly less in the affected-vertebrae fixation group than in the short-segment fixation group (P < 0.05). The affected-vertebrae fixation group had a lower mean graft fusion time (5.21 vs. 5.06 months), mean healing time (5.73 vs. 5.91 months), mean degree of correction of thoracic vertebrae kyphosis Cobb angle (16.9° vs. 18.4°), and mean loss of angle (2.6° vs. 2.1°) compared with the short-segment fixation group. However, these differences all lacked statistical significance. Postoperatively, neurological deficits and pain were effectively relieved in all patients, and the lesion had healed at the final follow-up evaluation (≥5 years postoperatively).

CONCLUSIONS

As long as the surgical indications are strictly observed, posterior affected-vertebrae fixation in posterior-anterior surgery for thoracic spinal tuberculosis is safe, effective, and feasible; entails minimal surgical trauma; and has a lower inpatient cost.

摘要

目的

进行本次回顾性对比分析,以评估病椎固定与短节段固定治疗胸椎结核的有效性。

方法

本研究纳入了2006年1月至2013年6月在我院接受胸椎结核治疗的110例患者。所有病例均采用后路脊柱矫正、后外侧融合、内固定、前路减压、彻底清创及椎间支撑植骨。根据后路内固定范围将病例分为病椎固定组(n = 62)和短节段固定组(n = 48)。采用统计学分析比较临床疗效、实验室检查结果及影像学表现。

结果

病椎固定组的平均手术失血量、平均手术时间及平均住院费用均显著低于短节段固定组(P < 0.05)。与短节段固定组相比,病椎固定组的平均植骨融合时间(5.21对5.06个月)、平均愈合时间(5.73对5.91个月)、胸椎后凸畸形Cobb角平均矫正度(16.9°对18.4°)及角度平均丢失(2.6°对2.1°)较低。然而,这些差异均无统计学意义。术后,所有患者的神经功能缺损和疼痛均得到有效缓解,且在末次随访评估(术后≥5年)时病变已愈合。

结论

只要严格遵守手术指征,在胸椎结核前后路手术中采用后路病椎固定是安全、有效且可行的;手术创伤最小;住院费用较低。

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