Shah Syed Yasir, Hadi Faiza Amatul, Idrees Muhammad, Levin-Carrion Yaxel, Pande Harshawardhan, Oorloff Melysze Deanne, Khan Qaisar Ali, Nadella Adithya
Khyber Teaching Hospital MTI KTH, Peshawar, Pakistan.
Mercer University School of Medicine, Macon, GA, USA.
Clin Med Insights Case Rep. 2023 May 28;16:11795476231178119. doi: 10.1177/11795476231178119. eCollection 2023.
Fahr's syndrome a rare neurological condition characterized by an abnormal basal ganglia calcification. The condition has both genetic and metabolic causes. Here, we describe a patient who had Fahr's syndrome and basal secondary to hypoparathyroidism, and her calcium level raised after the administration of steroid therapy.
We presented a case of a 23-year-old female with seizures. Associated symptoms included headache, vertigo, disturbed sleep, and reduced appetite. Her laboratory workup revealed hypocalcemia and low parathyroid hormone level, computed tomographic (CT) scan of the brain showed diffuse calcification in the brain parenchyma. The patient was diagnosed as a case of Fahr's syndrome secondary to hypoparathyroidism. The patient was started on calcium and calcium supplementations along with anti-seizure therapy. Her calcium level raised after the initiation of oral prednisolone and she remained asymptomatic.
Steroid could be considered as an adjunct therapy with calcium and vitamin D supplementation in patient whose Fahr's syndrome is secondary to primary hypoparathyroidism.
Fahr综合征是一种罕见的神经系统疾病，其特征为基底神经节异常钙化。该病症有遗传和代谢两种病因。在此，我们描述一名患有Fahr综合征且继发于甲状旁腺功能减退的患者，其在接受类固醇治疗后血钙水平升高。
我们报告一例23岁癫痫女性患者。相关症状包括头痛、眩晕、睡眠障碍和食欲减退。其实验室检查显示低钙血症和甲状旁腺激素水平降低，脑部计算机断层扫描（CT）显示脑实质弥漫性钙化。该患者被诊断为继发于甲状旁腺功能减退的Fahr综合征病例。患者开始接受钙剂和钙补充剂治疗以及抗癫痫治疗。口服泼尼松龙后其血钙水平升高，且患者无症状。
对于继发于原发性甲状旁腺功能减退的Fahr综合征患者，类固醇可被视为钙剂和维生素D补充剂的辅助治疗药物。
