Gauthier Laurent, Lafuma Antoine, Laurendeau Caroline, Berdeaux Gilles
Saint-Jean de Luz, Cemka-Eval, Paris, France.
J Cataract Refract Surg. 2010 Jul;36(7):1195-200. doi: 10.1016/j.jcrs.2010.01.027.
To compare 2-year neodymium:YAG (Nd:YAG) laser capsulotomy rates after bilateral implantation of hydrophobic or hydrophilic multifocal intraocular lenses (IOLs).
Private practice, southwest France.
This retrospective study included patients with cataract or clear lenses who had bilateral implantation of AcrySof ReSTOR hydrophobic or Acri.LISA hydrophilic acrylic multifocal IOLs between May 2004 and June 2009 by the same surgeon at 1 clinic. Data were extracted from patients' files maintained by the surgeon and ophthalmologists involved in postoperative care. Time from IOL implantation to Nd:YAG laser capsulotomy was analyzed with Kaplan-Meier survival curves. Imbalances in confounding variables were adjusted with a Cox model.
The hydrophobic IOL group comprised 80 patients and the hydrophilic IOL group, 76 patients. There were significantly more men in the hydrophobic group (51.3%) than in the hydrophilic group (30.7%) and patients were significantly younger in the hydrophobic group (63.0 years versus 65.8 years) (both P<.01). Eighteen months postoperatively, 4.4% of eyes in the hydrophobic group and 14.6% of eyes in the hydrophilic group required Nd:YAG laser capsulotomy. After 24 months, the respective rates were 8.8% and 37.2% (P<.0001). Eyes in the hydrophilic group had a 4.50-fold (2.28 versus 8.91) higher risk for Nd:YAG laser capsulotomy (P<.0001) that persisted after adjusting for age (relative risk 4.64, 2.32 to 9.29) (P<.0001). Patients younger than 63.5 years in the hydrophilic group were more likely to require Nd:YAG laser capsulotomy.
Capsulotomy was significantly less frequent after hydrophobic IOL implantation than after hydrophilic IOL implantation 24 months postoperatively.
No author has a financial or proprietary interest in any material or method mentioned. An additional disclosure is found in the footnotes.
比较双侧植入疏水性或亲水性多焦点人工晶状体（IOL）后2年钕:钇铝石榴石（Nd:YAG）激光晶状体囊切开术的发生率。
法国西南部的私人诊所。
这项回顾性研究纳入了2004年5月至2009年6月期间在一家诊所由同一位外科医生进行双侧植入AcrySof ReSTOR疏水性或Acri.LISA亲水性丙烯酸多焦点IOL的白内障或晶状体透明患者。数据从外科医生和参与术后护理的眼科医生保存的患者病历中提取。采用Kaplan-Meier生存曲线分析从IOL植入到Nd:YAG激光晶状体囊切开术的时间。用Cox模型调整混杂变量的不平衡。
疏水性IOL组有80例患者，亲水性IOL组有76例患者。疏水性组男性（51.3%）明显多于亲水性组（30.7%），且疏水性组患者明显更年轻（63.0岁对65.8岁）（均P<0.01）。术后18个月，疏水性组4.4%的眼和亲水性组14.6%的眼需要Nd:YAG激光晶状体囊切开术。24个月后，相应的发生率分别为8.8%和37.2%（P<0.0001）。亲水性组的眼发生Nd:YAG激光晶状体囊切开术的风险高4.50倍（2.28对8.91）（P<0.0001），在调整年龄后该风险仍然存在（相对风险4.64，2.32至9.29）（P<0.0001）。亲水性组中年龄小于63.5岁的患者更有可能需要Nd:YAG激光晶状体囊切开术。
术后24个月，植入疏水性IOL后晶状体囊切开术的发生率明显低于植入亲水性IOL后。
没有作者对文中提及的任何材料或方法有财务或专利权益。脚注中有额外的披露信息。
