Dias Andre, Núñez Gil Ivan J, Santoro Francesco, Madias John E, Pelliccia Francesco, Brunetti Natale Daniele, Salmoirago-Blotcher Elena, Sharkey Scott W, Eitel Ingo, Akashi Yoshihiro J, El-Battrawy Ibrahim, Franco Emiliana, Akin Ibrahim, Jaguszewski Milosz, Dawson Dana, Figueredo Vincent M, Napp L Christian, Christensen Thomas Emil, Hebert Kathy, Ben-Dor Itsik, Ozaki Yuichi, García-Garcia Héctor M, Kajita Alexandre H, Akasaka Takashi, Kurisu Satoshi, Lerman Amir, Waksman Ron
Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America; Department of Cardiology, Einstein Medical Center, Philadelphia, PA, United States of America.
Interventional Cardiology, Cardiovascular Institute, Hospital Clínico San Carlos, Madrid, Spain.
Cardiovasc Revasc Med. 2019 Jan;20(1):70-79. doi: 10.1016/j.carrev.2018.11.015. Epub 2018 Nov 17.
Takotsubo syndrome (TTS) is an acute cardiac condition independent of epicardial coronary obstruction that mimics acute coronary syndrome and is characterized by acute heart failure with reversible ventricular motion abnormalities. This consensus paper is the result of a multinational effort aiming to summarize the current state of the art on TTS. Experts in the field provide a thorough and detailed review of this syndrome. Several novel and unique sections are emphasized in this document, including the current state of the art on genetics of takotsubo syndrome, microRNAs (miRs), racial differences, role of cardiac spectroscopy and intracoronary imaging, as well as mechanical circulatory support. In part 1 of this two-part manuscript, we discuss how TTS came to be known, several patterns and forms it can take in patients, epidemiology and pathophysiology of the syndrome, and clinical presentation.
应激性心肌病（TTS）是一种独立于冠状动脉阻塞的急性心脏疾病，它酷似急性冠脉综合征，其特征是急性心力衰竭伴可逆性心室运动异常。本共识文件是一项多国合作的成果，旨在总结应激性心肌病的当前技术水平。该领域的专家对这一综合征进行了全面而详细的综述。本文强调了几个新颖独特的部分，包括应激性心肌病遗传学、微小RNA（miRs）、种族差异、心脏光谱学和冠状动脉内成像的当前技术水平，以及机械循环支持。在这份两部分手稿的第1部分中，我们讨论了应激性心肌病是如何为人所知的、它在患者中可能呈现的几种模式和形式、该综合征的流行病学和病理生理学，以及临床表现。
