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DREAMS 核心干预包:预防少女和年轻妇女感染艾滋病毒的综合方法。

The DREAMS core package of interventions: A comprehensive approach to preventing HIV among adolescent girls and young women.

机构信息

Office of the U.S. Global AIDS Coordinator and Health Diplomacy, U.S. Department of State, Washington, DC, United States of America.

出版信息

PLoS One. 2018 Dec 7;13(12):e0208167. doi: 10.1371/journal.pone.0208167. eCollection 2018.

DOI:10.1371/journal.pone.0208167
PMID:30532210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6285267/
Abstract

In sub-Saharan Africa, adolescent girls and young women (AGYW) are 5 to 14 times more likely to be infected with HIV than their male peers. Every day, more than 750 AGYW are infected with HIV. Many factors make girls and young women particularly vulnerable to HIV, including gender-based violence, exclusion from economic opportunities, and a lack of access to secondary school. The President's Emergency Plan for AIDS Relief (PEPFAR) is dedicating significant resources through the Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe (DREAMS) partnership to impact the lives of women and girls based on PEPFAR's mission to help countries achieve epidemic control of HIV/AIDS. The data show that new HIV infections must be reduced in AGYW, or the global community risks losing the extensive progress made towards reaching epidemic control. With support from PEPFAR and private sector partners-the Bill & Melinda Gates Foundation, Gilead Sciences, Girl Effect, Johnson & Johnson and ViiV Healthcare, DREAMS works together with partner governments to deliver a core package of interventions that combines evidence-based approaches that go beyond the health sector, addressing the structural drivers that directly and indirectly increase girls' HIV risk. Not only is DREAMS an effort to reduce new HIV infections, but it aims to reduce other critical vulnerabilities such as gender-based violence. When girls and young women thrive, the effects are felt throughout their families, communities and countries.

摘要

在撒哈拉以南非洲,少女和年轻妇女(AGYW)感染艾滋病毒的可能性比同龄男性高 5 到 14 倍。每天,都有超过 750 名 AGYW 感染艾滋病毒。许多因素使女孩和年轻妇女特别容易感染艾滋病毒,包括性别暴力、被排除在经济机会之外以及缺乏接受中学教育的机会。总统艾滋病紧急救援计划(PEPFAR)通过坚定、有韧性、赋权、无艾滋病、有指导和安全(DREAMS)伙伴关系投入大量资源,根据 PEPFAR 帮助各国实现艾滋病毒/艾滋病流行控制的使命,影响妇女和女孩的生活。数据显示,必须减少 AGYW 中的新艾滋病毒感染,否则全球社会有可能失去在实现流行控制方面取得的广泛进展。在 PEPFAR 和私营部门合作伙伴——比尔及梅琳达·盖茨基金会、吉利德科学公司、女孩效应、强生公司和 ViiV 医疗保健公司的支持下,DREAMS 与伙伴政府合作,提供一整套核心干预措施,这些措施结合了超越卫生部门的循证方法,解决直接和间接增加女孩艾滋病毒风险的结构性驱动因素。DREAMS 不仅旨在减少新的艾滋病毒感染,还旨在减少其他关键脆弱性,如性别暴力。当女孩和年轻妇女茁壮成长时,其影响将在整个家庭、社区和国家中感受到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f6/6285267/d04ace8fba54/pone.0208167.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f6/6285267/d246c8bdb7ad/pone.0208167.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f6/6285267/d04ace8fba54/pone.0208167.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f6/6285267/d246c8bdb7ad/pone.0208167.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2f6/6285267/d04ace8fba54/pone.0208167.g002.jpg

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Brief Report: Preventing HIV-1 Infection in Women Using Oral Preexposure Prophylaxis: A Meta-analysis of Current Evidence.
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