Morigami Yuko, Ono Koh, Jinnai Toshikazu, Tamura Toshihiro, Watanabe Shin, Takai Fumie, Osada Hiroaki, Yamazaki Kazuhiro, Kita Toru, Sakata Ryuzo, Kimura Takeshi
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
J Cardiol Cases. 2011 Aug 11;4(2):e76-e79. doi: 10.1016/j.jccase.2011.07.004. eCollection 2011 Oct.
Behçet's disease is a chronic, relapsing, multi-systemic inflammatory disorder characterized by recurrent orogenital aphthous ulcers, uveitis, and skin lesions. Vascular involvement affects the veins more commonly than the arteries of these patients. Arterial involvement may include aneurysm formation, occlusive disease, and stenosis, with the most common sites being the abdominal aorta and femoral and pulmonary arteries. Thus, coronary arterial involvement is very rare but can cause serious complications when it occurs. In this report, we present a 28-year-old male patient with Behçet's disease who developed a giant right coronary artery aneurysm with minimal cardiac manifestation of a recently developed slight palpitation. The patient underwent surgical repair. We present the results of cardiovascular imaging and histopathological examinations. Our case demonstrates the necessity of regular cardiovascular examination for patients with Behçet's disease, even for those without cardiac symptoms.
白塞病是一种慢性、复发性、多系统炎症性疾病,其特征为复发性口腔和生殖器阿弗他溃疡、葡萄膜炎及皮肤病变。这些患者血管受累时,静脉比动脉更常受到影响。动脉受累可能包括动脉瘤形成、闭塞性疾病和狭窄,最常见的部位是腹主动脉、股动脉和肺动脉。因此,冠状动脉受累非常罕见,但一旦发生可导致严重并发症。在本报告中,我们介绍了一名28岁患有白塞病的男性患者,该患者出现了巨大的右冠状动脉瘤,近期仅表现为轻微心悸这一极为轻微的心脏症状。该患者接受了手术修复。我们展示了心血管成像和组织病理学检查的结果。我们的病例表明,对白塞病患者,即使是没有心脏症状的患者,进行定期心血管检查也是必要的。