Int Dent J. 1988 Sep;38(3):177-89.
The search for methods of predicting dental caries activity began during the last century. The purpose of this review was to update the report on methods of caries prediction which resulted from the 1977 workshop, sponsored by the National Institutes of Health, Washington, DC, and also to identify the methods most likely to provide effective prediction of caries risk which should be given high priority in future research. The factors that need to be considered in assessing the value of a method of predicting caries risk are the correlation coefficient between the predictions and the final caries scores and in particular an assessment of the ability of the method to recognize subjects who will develop caries (sensitivity) and to exclude those who will not (specificity). The predictive power of the method should also be known. There is, however, the risk that when predictive tests are applied to a population with decreasing caries prevalence the number classified as false positive could be increased. This may limit the cost-effectiveness of preventive technique. The requirements of a good method of predicting dental caries are that the method should be simple, inexpensive and rapid and should identify subjects who will become diseased and exclude subjects who will remain healthy. To date, a wide variety of factors have been considered in the search for an effective method of predicting caries risk, but only a few have had some success. Certain epidemiological methods have shown reasonable sensitivity but less specificity. Measures in this category include specific indicator surfaces and DMFT increment in the previous year. Among the more useful specific tests have been mutans streptococci and lactobacillus counts and measurement of saliva buffering capacity. Other methods that show some promise include the physical measurement of incipient carious lesions of enamel. The measurement of possible determinants of a multifactorial disease is extremely difficult and regardless of which single method has been tried the authors have usually concluded that it is difficult to develop a reliable method of identifying caries susceptible individuals from the method. To a lesser extent the same conclusions have been applied to methods for identifying risk groups. There does, however, appear to have been little research in which a combination of tests or methods have been used, particularly combinations of tests that involve different scientific disciplines.(ABSTRACT TRUNCATED AT 400 WORDS)
对龋齿活动预测方法的探索始于上世纪。本综述的目的是更新由华盛顿特区国立卫生研究院赞助的1977年研讨会所产生的龋齿预测方法报告,同时确定最有可能有效预测龋齿风险的方法,这些方法应在未来研究中得到高度重视。在评估一种龋齿风险预测方法的价值时,需要考虑的因素包括预测结果与最终龋齿评分之间的相关系数,特别是对该方法识别将患龋齿的受试者(敏感性)和排除不会患龋齿的受试者(特异性)能力的评估。还应了解该方法的预测能力。然而,存在这样一种风险,即当将预测测试应用于龋齿患病率不断下降的人群时,被归类为假阳性的人数可能会增加。这可能会限制预防技术的成本效益。一种好的龋齿预测方法的要求是该方法应简单、廉价且快速,并且应识别出将患病的受试者并排除将保持健康的受试者。迄今为止,在寻找有效的龋齿风险预测方法的过程中,已经考虑了各种各样的因素,但只有少数取得了一些成功。某些流行病学方法显示出合理的敏感性,但特异性较低。这一类措施包括特定的指示表面和上一年的龋失补牙面增量。在更有用的特定测试中,有变形链球菌和乳酸杆菌计数以及唾液缓冲能力的测量。其他显示出一定前景的方法包括对早期釉质龋损的物理测量。对一种多因素疾病的可能决定因素进行测量极其困难,无论尝试哪种单一方法,作者通常都得出结论,很难从该方法中开发出一种可靠的识别龋齿易感个体的方法。在较小程度上,同样的结论也适用于识别风险群体的方法。然而,似乎很少有研究使用测试或方法的组合,特别是涉及不同科学学科的测试组合。(摘要截选至400字)