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卡罗来纳鼠李树皮中的植物化学物质。

Phytochemicals from the Bark of Rhamnus caroliniana.

作者信息

Mekala Amrutha Bindu, Satyal Prabodh, Setzer William N

出版信息

Nat Prod Commun. 2017 Mar;12(3):403-406.

PMID:30549896
Abstract

Rhamnus caroliniana (Rhamnaceae), or Carolina buckthorn, is a plant commonly found in the southeastern United States that was used in Cherokee traditional medicine. To date, there have been no reports on the phytochemical constituents of R. caroliniana. The bark of R. caroliniana was collected and extracted with chloroform. The crude chloroform extract was subjected to preparative column chromatography on silica gel leading to the isolation of two anthraquinones (chrysophanol and physcion), the bianthrone ararobinol, the dihydroxynaphthalene torachrysone, and the fatty alcohol 1-docosanol. The bark essential oil of R. caroliniana was obtained by hydrodistillation and analyzed by gas chromatography - mass spectrometry. The major bark volatiles were the anthrone chrysarobin-(24.2%), the piperidine alkaloid piperine (15.4%), and the dibenzoxepin pacharin (7.5%).

摘要

卡罗莱纳鼠李(鼠李科),即卡罗莱纳鼠李,是一种常见于美国东南部的植物,曾被用于切罗基族传统医学。迄今为止,尚未有关于卡罗莱纳鼠李植物化学成分的报道。采集了卡罗莱纳鼠李的树皮并用氯仿进行提取。将粗制氯仿提取物在硅胶上进行制备柱色谱分离,得到了两种蒽醌(大黄酚和大黄素甲醚)、双蒽酮阿劳波醇、二羟基萘托酚酮以及脂肪醇1-二十二醇。通过水蒸馏法获得了卡罗莱纳鼠李树皮精油,并采用气相色谱-质谱联用仪进行分析。树皮中的主要挥发成分是蒽酮驱虫豆素(24.2%)、哌啶生物碱胡椒碱(15.4%)和二苯并氧杂卓帕查林(7.5%)。

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