Lawson Sims K, Sharp Layla G, Powers Chelsea N, McFeeters Robert L, Satyal Prabodh, Setzer William N
Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA.
Aromatic Plant Research Center, 230 N 1200 E, Suite 100, Lehi, UT 84043, USA.
Plants (Basel). 2020 Jan 19;9(1):126. doi: 10.3390/plants9010126.
In the past, Native Americans of North America had an abundant traditional herbal legacy for treating illnesses, disorders, and wounds. Unfortunately, much of the ethnopharmacological knowledge of North American Indians has been lost due to population destruction and displacement from their native lands by European-based settlers. However, there are some sources of Native American ethnobotany remaining. In this work, we have consulted the ethnobotanical literature for members of the Asteraceae used in Cherokee and other Native American traditional medicines that are native to the southeastern United States. The aerial parts of , , , , , , , , and were collected from wild-growing plants in north Alabama. The plants were hydrodistilled to obtain the essential oils and the chemical compositions of the essential oils were determined by gas chromatography-mass spectrometry. The essential oils were tested for in-vitro antifungal activity against , , and . The essential oil of showed noteworthy activity against with a minimum inhibitory concentration (MIC) value of 78 μg/mL, which can be attributed to the high concentration of cyclocolorenone in the essential oil.
过去，北美原住民拥有丰富的传统草药遗产用于治疗疾病、失调和伤口。不幸的是，由于人口遭到破坏以及被欧洲定居者赶出故土，北美印第安人的许多民族药理学知识已经失传。然而，仍有一些北美原住民民族植物学的资料留存。在这项研究中，我们查阅了民族植物学文献，了解菊科植物中用于切罗基族和其他原产于美国东南部的美洲原住民传统药物的植物。[此处原文列举了多种植物名称，未给出具体中文，无法准确翻译]的地上部分是从阿拉巴马州北部的野生植物中采集的。将这些植物进行水蒸馏以获得精油，并通过气相色谱 - 质谱联用仪测定精油的化学成分。对这些精油进行了针对[此处原文列举了多种真菌名称，未给出具体中文，无法准确翻译]的体外抗真菌活性测试。[某种植物名称]的精油对[某种真菌名称]表现出显著活性，最低抑菌浓度（MIC）值为78μg/mL，这可归因于该精油中高浓度的环环烯醚萜酮。
