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《山竹子(藤黄科)的植物成分与生物活性综述》

Phytoconstituents and Biological Activities of Garcinia dulcis (Clusiaceae): A Review.

作者信息

Khamthong Nanthaphong, Hutadilok-Towatana Nongporn

出版信息

Nat Prod Commun. 2017 Mar;12(3):453-460.

PMID:30549909
Abstract

Garcinia dulcis (Roxb.) Kurz is a tropical fruit tree native to Southeast Asia where it has a long history of use as a traditional medicine for the treatment of ailments such as lymphatitis, parotitis, struma, scurvy, cough, and sore throat. Despite its medicinal values, this plant is not well known and rarely found nowadays. Research on the phytochemical constituents and biological activities of G. dulcis have demonstrated that various parts of the plant contain an. abundance of bioactive compounds mainly xanthones and flavonoids, with significant pharmacological properties such as anti-atherosclerosis, anti-bacterial, anti-cancer, anti-hypertension, and anti-malarial. In the present review, current knowledge of the phytochemistry of G. dulcis and biological activities of its active constituents based on the available literature are summarized in order to explore application potentials and prospective research works on this plant.

摘要

滇南藤黄(Garcinia dulcis (Roxb.) Kurz)是一种热带果树,原产于东南亚,在当地作为传统药物治疗诸如淋巴管炎、腮腺炎、甲状腺肿、坏血病、咳嗽和喉咙痛等疾病已有悠久历史。尽管具有药用价值,但这种植物如今并不广为人知且很少见。对滇南藤黄植物化学成分和生物活性的研究表明,该植物的各个部位都含有丰富的生物活性化合物,主要是氧杂蒽酮和黄酮类化合物,具有显著的药理特性,如抗动脉粥样硬化、抗菌、抗癌、抗高血压和抗疟疾。在本综述中,基于现有文献总结了滇南藤黄植物化学的当前知识及其活性成分的生物活性,以探索该植物的应用潜力和未来研究工作。

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