Junaid Muhammad, Rashid Mamoon Ur, Bukhari Syed Sarmad, Ahmed Mamoon
Dr. Muhammad Junaid, FCPS. Associate Professor Head of Neurosurgery, PNS Shifa, Karachi, Pakistan.
Dr. Mamoon Ur Rashid, MBBS. Department of Internal Medicine, Orlando Hospital, Orlando, FL, USA.
Pak J Med Sci. 2018 Nov-Dec;34(6):1412-1417. doi: 10.12669/pjms.346.15833.
To study clinical and radiological outcomes in patients who had undergone the procedure of anterior cervical discectomy and fusion with titanium or PEEK (polyetheretherketone) cages for cervical disc prolapse.
This is a retrospective/non-randomized study which was conducted at the Combined Military Hospital Peshawar. Study interval was four years from 1st October, 2010 to 31st September, 2014. Total number of included patients were 149. All of the patients had undergone the procedure of anterior cervical discectomy and fusion with titanium or PEEK (polyetheretherketone) cages. All of the patients had plain MRI cervical spine done for diagnosis of anterior cervical disc prolapse.
Most of the patients had stenosis at the C5 / C6 (PEEK cage group 63% and titanium cage group 47.6%) and C6 / C7 (PEEK cage group 15.38% and titanium cage group 19.04%) cervical level. Bi-level involvement was also seen. In the patients who complained of brachialgia, total resolution of symptoms was seen after the operation. Three (2.01%) of the patients in titanium cage group, who presented with axial neck pain, continued to complain of pain after the operation. Four (2.6%) of the patients in PEEK (polyetheretherketone) cage group and 2 (1.3%) in titanium cage group complained of pain at the donor site (iliac crest). Fusion rate was 100% with both titanium and PEEK (polyetheretherketone) cages at one year.
Results with titanium and PEEK (polyetheretherketone) cages are excellent. There was no significant difference in clinical and radiological outcome between two groups of patients (p > 0.05). Fusion rate was 100% at one year with both cages.
研究因颈椎间盘突出症接受颈椎前路椎间盘切除融合钛笼或聚醚醚酮（PEEK）笼手术患者的临床和影像学结果。
这是一项在白沙瓦联合军事医院进行的回顾性/非随机研究。研究时间跨度为2010年10月1日至2014年9月31日的四年。纳入患者总数为149例。所有患者均接受了颈椎前路椎间盘切除融合钛笼或聚醚醚酮（PEEK）笼手术。所有患者均进行了颈椎平扫MRI以诊断颈椎前路椎间盘突出症。
大多数患者在C5/C6（PEEK笼组63%，钛笼组47.6%）和C6/C7（PEEK笼组15.38%，钛笼组19.04%）颈椎节段存在狭窄。也可见双节段受累。在主诉臂痛的患者中，术后症状完全缓解。钛笼组中有3例（2.01%）出现颈部轴向疼痛的患者术后仍持续疼痛。PEEK（聚醚醚酮）笼组中有4例（2.6%）患者和钛笼组中有2例（1.3%）患者主诉供骨部位（髂嵴）疼痛。钛笼和PEEK（聚醚醚酮）笼在一年时的融合率均为100%。
钛笼和PEEK（聚醚醚酮）笼的效果极佳。两组患者在临床和影像学结果上无显著差异（p>0.05）。两种笼子在一年时的融合率均为100%。
