Research Division, Epidemiology Service, Assuta Medical Centers, Tel Aviv, Israel.
Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, 6997801, Ramat Aviv, Tel Aviv, Israel.
Dig Dis Sci. 2019 May;64(5):1288-1295. doi: 10.1007/s10620-018-5352-5. Epub 2018 Dec 18.
Bloating is one of the most bothersome symptoms of irritable bowel syndrome (IBS), but its association with other symptoms is not well described.
We investigated the association between symptoms of abdominal bloating, other IBS symptoms, psychological distress, and comorbid pain conditions.
We conducted a cross-sectional study on a large cohort of IBS patients with and without symptoms of abdominal bloating and healthy controls. Subjects were assessed for IBS and its subtypes, pain severity, symptoms severity, psychological disturbances, comorbidities, and dietary restrictions of three fluid groups.
A total of 484 subjects were investigated. Compared with IBS - B, IBS + B subjects had higher rates of constipation (30% vs. 15%, p = 0.191) and lower rates of diarrhea, (70% vs. 85%, p = 0.191) although these were not statistically significant. Bloating severity correlated with IBS symptoms severity (r = 0.397, p = 0.000), pain severity (r = 0.364, p = 0.000), and both anxiety and somatization scores (r = 0.167, p = 0.015 and r = 0.219, p = 0.001, respectively). Prevalence of fibromyalgia and depression and somatization scores was significantly higher in IBS with bloating than in IBS without bloating. IBS patients with bloating reported more dietary restriction of three fluid groups to control their symptoms compared with healthy controls and IBS patients without bloating.
Abdominal bloating in IBS is associated with increased symptoms and pain severity, somatization, depression, fibromyalgia, and altered dietary fluids composition. Recognizing and addressing these factors in the diagnosis and management of patients with IBS may improve clinical outcome.
腹胀是肠易激综合征（IBS）最恼人的症状之一，但它与其他症状的关系尚未得到很好的描述。
我们研究了腹胀症状与其他 IBS 症状、心理困扰和并存疼痛状况之间的关系。
我们对有和无腹胀症状的 IBS 患者以及健康对照组进行了一项横断面研究。评估了患者的 IBS 及其亚型、疼痛严重程度、症状严重程度、心理障碍、并存疾病以及三组液体的饮食限制。
共调查了 484 名受试者。与 IBS-B 相比，IBS+B 患者的便秘发生率更高（30% vs. 15%，p=0.191），腹泻发生率更低（70% vs. 85%，p=0.191），但无统计学意义。腹胀严重程度与 IBS 症状严重程度（r=0.397，p=0.000）、疼痛严重程度（r=0.364，p=0.000）以及焦虑和躯体化评分（r=0.167，p=0.015 和 r=0.219，p=0.001）相关。腹胀的 IBS 患者比无腹胀的 IBS 患者更易发生纤维肌痛和抑郁，躯体化评分也更高。与健康对照组和无腹胀的 IBS 患者相比，腹胀的 IBS 患者报告为控制症状而限制三组液体的饮食更多。
IBS 中的腹胀与症状和疼痛严重程度、躯体化、抑郁、纤维肌痛以及改变的饮食液体组成增加有关。在 IBS 患者的诊断和管理中认识并处理这些因素可能会改善临床结果。
