Geremew Demeke, Tajebe Fitsumbrhan, Ambachew Sintayehu, Endalamaw Aklilu, Eshetie Setegn
Department of Immunology and Molecular Biology, School of Biomedical and Laboratory Sciences, University of Gondar, P.o.Box: 196, Gondar, Ethiopia.
Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, University of Gondar, Gondar, Ethiopia.
BMC Res Notes. 2018 Dec 19;11(1):908. doi: 10.1186/s13104-018-4022-1.
This systematic review and meta-analysis aimed to determine the pooled prevalence of HIV among pregnant women in Ethiopia.
PubMed, EMBASE, Science Direct and Google scholar databases were searched to retrieve 15 relevant articles based on the inclusion criteria. A total of 13,746 participants were included in the original studies and considered in this analysis. Among subjects, 717 were infected with HIV only, and 12 were HIV-HBV co-infected pregnant women. In this meta-analysis, the pooled prevalence of HIV among pregnant women in Ethiopia was 5.74% (95% CI 3.96-7.53%). Regional analysis showed that 9.50% (95% CI 7.76-11.23%) in Amhara, 4.80% (95% CI 3.12-6.49%) in Addis Ababa, 2.14% (95% CI - 0.54 to 4.82%) in SNNP and 4.48% (95% CI 2.56-6.41%) in Oromia region. Besides, six studies reported HIV-HBV co-infection and the pooled prevalence was 0.68% (95% CI 0.27-1.08%) among pregnant women in Ethiopia.
本系统评价和荟萃分析旨在确定埃塞俄比亚孕妇中艾滋病毒的合并患病率。
检索了PubMed、EMBASE、Science Direct和谷歌学术数据库，根据纳入标准检索到15篇相关文章。原始研究共纳入13746名参与者并纳入本分析。在这些受试者中，717人仅感染艾滋病毒，12人是艾滋病毒和乙肝病毒合并感染的孕妇。在这项荟萃分析中，埃塞俄比亚孕妇中艾滋病毒的合并患病率为5.74%（95%置信区间3.96 - 7.53%）。区域分析显示，阿姆哈拉地区为9.50%（95%置信区间7.76 - 11.23%），亚的斯亚贝巴为4.80%（95%置信区间3.12 - 6.49%），南方各族州为2.14%（95%置信区间 - 0.54至4.82%），奥罗米亚地区为4.48%（95%置信区间2.56 - 6.41%）。此外，六项研究报告了艾滋病毒和乙肝病毒合并感染情况，埃塞俄比亚孕妇中的合并患病率为0.68%（95%置信区间0.27 - 1.08%）。
