Ishikawa Sho, Kato Naoko, Takeuchi Masaru
Department of Ophthalmology, Saitama Medical University, 38 Morohongo, Moroyama, Saitama, 350-0495, Japan.
Department of Ophthalmology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8216, Japan.
BMC Ophthalmol. 2018 Dec 20;18(1):334. doi: 10.1186/s12886-018-0998-5.
The optical density of the cornea can be evaluated quantitatively by "densitometry" using a rotating Scheimpflug camera. Densitometry allows evaluation of corneal opacity in the anterior segment of the eye by quantitative measurement of scattering light. In the present investigation, we evaluate quantitatively minimal subclinical corneal edema after cataract surgery using densitometry.
Fifty four eyes of 34 patients who underwent cataract surgery were enrolled. Measurement of corneal density was performed using Pentacam® before and on days 1, 3 and 7 after surgery.
Densitometry scores increased from 18.12 ± 1.76 before cataract surgery to 21.03 ± 3.84 on day 1 (P < 0.001) and 19.90 ± 2.46 on day 3 (P = 0.018), but recovered to 19.44 ± 1.58 on day 7 (P = 0.131). Total corneal thickness was 549.1 ± 32.7 μm before surgery and increased to 582.7 ± 46.3 μm on day 1 (P = 0.001), but recovered to 566.4 ± 29.7 μm on day 3 (P = 0.097). Densitometry reading correlated positively with corneal thickness (correlation coefficient = 0.13, P = 0.003).
Densitometry is useful to detect corneal edema that is not detectable by slit-lamp examination.
使用旋转式Scheimpflug相机通过“密度测定法”可对角膜的光密度进行定量评估。密度测定法能够通过对散射光的定量测量来评估眼前节的角膜混浊情况。在本研究中,我们使用密度测定法对白内障手术后最小程度的亚临床角膜水肿进行了定量评估。
纳入34例接受白内障手术患者的54只眼。在手术前以及术后第1天、第3天和第7天使用Pentacam®测量角膜密度。
密度测定评分从白内障手术前的18.12±1.76增加至术后第1天的21.03±3.84(P<0.001)以及第3天的19.90±2.46(P=0.018),但在第7天恢复至19.44±1.58(P=0.131)。术前角膜总厚度为549.1±32.7μm,术后第1天增加至582.7±46.3μm(P=0.001),但在第3天恢复至566.4±29.7μm(P=0.097)。密度测定读数与角膜厚度呈正相关(相关系数=0.13,P=0.003)。
密度测定法有助于检测裂隙灯检查无法发现的角膜水肿。