Åstrøm Anne N, Lie Stein A, Ekback Gunnar, Gülcan Ferda, Ordell Sven
Department of Clinical Dentistry, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway.
Örebro County Council, Örebro, Sweden.
Eur J Oral Sci. 2019 Apr;127(2):130-138. doi: 10.1111/eos.12601. Epub 2018 Dec 25.
Focusing on Swedish and Norwegian cohorts of community-dwelling older adults between age 65 and 70, this study aimed to identify predictors of the prevalence and incident cases of daytime and night-time xerostomia. It was hypothesized that the prevalence increases with increasing age and is higher in women than in men and that the prevalence of persistent xerostomia and the 5-yr-incident cases are higher in people with consistent use of medication and need for health care. Of the Norwegian participants who completed the 2007 survey (age 65 yr), 70% (n = 2,947) participated in 2012. Individuals participating in both 2007 and 2012 constituted the Swedish panel (80%, n = 4,862). The prevalence of xerostomia was higher in women than in men and increased from age 65 to age 70, most markedly in the Swedish cohort. The risk of persistent xerostomia was greatest for participants with consistent use of medication (OR = 1.3) and contact with a physician (OR = 2.3). The risk of incident cases of xerostomia during daytime was greatest for participants with recent and consistent use of medication and recent contact with a physician. Dental professionals should identify patients with xerostomia, emphasize early prevention, and alleviate oral symptoms in collaboration with physicians.
本研究聚焦于年龄在65至70岁之间的瑞典和挪威社区居住老年人队列,旨在确定白天和夜间口干症患病率及发病病例的预测因素。研究假设患病率随年龄增长而增加,女性高于男性,且持续使用药物和需要医疗保健的人群中,持续性口干症的患病率和5年发病病例更高。在完成2007年调查(65岁)的挪威参与者中,70%(n = 2947)在2012年参与了调查。同时参与2007年和2012年调查的个体构成了瑞典样本(80%,n = 4862)。女性口干症患病率高于男性,且从65岁至70岁有所增加,在瑞典队列中最为明显。持续使用药物的参与者(OR = 1.3)和与医生接触的参与者(OR = 2.3)患持续性口干症的风险最大。近期持续使用药物且近期与医生接触的参与者白天患口干症发病病例的风险最大。牙科专业人员应识别口干症患者,强调早期预防,并与医生合作缓解口腔症状。