Więch Paweł, Sałacińska Izabela, Bazaliński Dariusz, Dąbrowski Mariusz
Institute of Nursing and Health Sciences, Faculty of Medicine, University of Rzeszów, Al. mjr. W. Kopisto 2 a, 35-310, Rzeszów, Poland.
Diabetic Outpatient Clinic, Medical Center "Beta-Med", Pl. Wolności 17, 35-073, Rzeszów, Poland.
Pediatr Rheumatol Online J. 2018 Dec 27;16(1):82. doi: 10.1186/s12969-018-0297-y.
Juvenile idiopathic arthritis (JIA) is the most common chronic, systemic autoimmune connective tissue disease diagnosed in children and adolescents. An important aspect of monitoring of children with JIA is a precise assessment of the nutritional status to identify children and adolescents at risk of malnutrition. The aim of the study was to assess the body composition and phase angle in children diagnosed with JIA in comparison to age and sex matched healthy children since there are scarce reports in paediatric patients.
A total of 46 children and adolescents aged 4-18 years, with JIA were included in the cross-sectional study. Controls were selected from the group of healthy children and adolescents. Children with diagnosed JIA and healthy children were strictly matched for age and gender. In both groups BIA with phase angle calculation was performed.
Phase angle score was significantly lower in the study group compared to control group (5.45 ± 0.64 vs. 5.85 ± 0.80, p = 0.010). Also lower percentage of body cell mass (50.63 ± 3.46 vs. 52.70 ± 4.06, p = 0.010) and muscle mass (46.02 ± 6.32 vs. 49.53 ± 6.67, p = 0.005) were revealed. In the analysis of subtypes of JIA we found significant differences between children and adolescents with polyarthritis compared to control group, while no significant differences were found between patients with oligoarthritis and control group.
The obtained results indicate a higher risk of malnutrition in children and adolescents with JIA compared to healthy peers, predominantly in patients with polyarthritis.
幼年特发性关节炎（JIA）是儿童和青少年中最常见的慢性全身性自身免疫性结缔组织疾病。对JIA患儿进行监测的一个重要方面是精确评估营养状况，以识别有营养不良风险的儿童和青少年。由于儿科患者的相关报道较少，本研究旨在评估JIA患儿与年龄和性别匹配的健康儿童的身体成分和相位角。
本横断面研究共纳入46例4 - 18岁的JIA患儿和青少年。对照组从健康儿童和青少年组中选取。确诊为JIA的儿童和健康儿童在年龄和性别上进行严格匹配。两组均进行了带相位角计算的生物电阻抗分析（BIA）。
研究组的相位角评分显著低于对照组（5.45±0.64 vs. 5.85±0.80，p = 0.010）。身体细胞质量百分比（50.63±3.46 vs. 52.70±4.06，p = 0.010）和肌肉质量（46.02±6.32 vs. 49.53±6.67，p = 0.005）也较低。在JIA亚型分析中，我们发现多关节炎患儿与青少年与对照组相比存在显著差异，而少关节炎患者与对照组之间未发现显著差异。
所得结果表明，与健康同龄人相比，JIA患儿和青少年营养不良风险更高，主要是多关节炎患者。
