SMILES 试验：不公开的招募实践是否可以解释如此显著的效果？
The SMILES trial: do undisclosed recruitment practices explain the remarkably large effect?
机构信息
Institute of Psychology, Clinical Psychology Unit, Leiden University, Leiden, The Netherlands.
Leiden Institute of Brain and Cognition, Leiden University Medical Center, Leiden, The Netherlands.
出版信息
BMC Med. 2018 Dec 28;16(1):243. doi: 10.1186/s12916-018-1221-5.
Abstract
The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the observed effect.
摘要
SMILES 试验表明，经过七次关于健康饮食的咨询，抑郁症状有了显著改善。在降低抑郁方面的效果非常显著，我们认为选择性诱导的期望和失去盲法可能对观察到的效果有贡献。
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