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[紫檀芪在癌症研究中的新作用]

[Emerging Actions of Pterostilebene on Cancer Research].

作者信息

Zhang Xiaoyan, Zhang Jiao, Xu Liqun, Ma Zhiqiang, Di Shouyin, Gao Yuan, Li Xiaofei, Yan Xiaolong, Zhang Hongmei

机构信息

Department of Clinical Oncology, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China.

Department of Thoracic Surgery, Tangdu Hospital, the Fourth Military Medical University, Xi'an 710038, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2018 Dec 20;21(12):931-936. doi: 10.3779/j.issn.1009-3419.2018.12.01.


DOI:10.3779/j.issn.1009-3419.2018.12.01
PMID:30591102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6318568/
Abstract

Pterostilbene (3,5-dimethoxy-4'-hydroxystilbene) is a polyphenolic compound primarily found in blueberries, grapes, and a tree wood, pterocarpus marsupium. Studies demonstrate that pterostilbene inhibits a variety of cancers, such as lung, breast, stomach, colon, etc. The anti-cancer activities are related to the regulation of several hallmarks of cancer. Moreover, pterostilbene exhibits much greater bioavailability and bioactivity than resveratrol which warrants further investigation in the anti-cancer functions and mechanisms.
.

摘要

紫檀芪(3,5 - 二甲氧基 - 4'- 羟基芪)是一种主要存在于蓝莓、葡萄以及一种树木——印度紫檀中的多酚类化合物。研究表明,紫檀芪能抑制多种癌症,如肺癌、乳腺癌、胃癌、结肠癌等。其抗癌活性与癌症的几个特征的调节有关。此外,紫檀芪比白藜芦醇具有更高的生物利用度和生物活性,这值得在抗癌功能和机制方面进行进一步研究。

相似文献

[1]
[Emerging Actions of Pterostilebene on Cancer Research].

Zhongguo Fei Ai Za Zhi. 2018-12-20

[2]
Occurrence, Bioavailability, Anti-inflammatory, and Anticancer Effects of Pterostilbene.

J Agric Food Chem. 2020-11-18

[3]
Pterostilbene and cancer: current review.

J Surg Res. 2011-10-21

[4]
In vitro evaluation of the cytotoxic, anti-proliferative and anti-oxidant properties of pterostilbene isolated from Pterocarpus marsupium.

Toxicol In Vitro. 2010-2-10

[5]
[Resveratrol--evaluation of anticancer activity].

Pol Merkur Lekarski. 2006-3

[6]
Determining the Effect of Pterostilbene on Insulin Secretion Using Chemoproteomics.

Molecules. 2020-6-23

[7]
Selective COX-2 inhibition by a Pterocarpus marsupium extract characterized by pterostilbene, and its activity in healthy human volunteers.

Planta Med. 2005-5

[8]
A new dimeric resveratrol from the roots of Shorea roxburghii.

Fitoterapia. 2011-1-14

[9]
Resveratrol and other Stilbenes: Effects on Dysregulated Gene Expression in Cancers and Novel Delivery Systems.

Anticancer Agents Med Chem. 2021

[10]
Regulation of cell death and survival by resveratrol: implications for cancer therapy.

Anticancer Agents Med Chem. 2012-10-1

引用本文的文献

[1]
Association between Polyphenol Intake and Gastric Cancer Risk by Anatomic and Histologic Subtypes: MCC-Spain.

Nutrients. 2020-10-26

本文引用的文献

[1]
Biological actions and molecular effects of resveratrol, pterostilbene, and 3'-hydroxypterostilbene.

J Food Drug Anal. 2016-9-22

[2]
Autophagy-inducing effect of pterostilbene: A prospective therapeutic/preventive option for skin diseases.

J Food Drug Anal. 2016-12-11

[3]
Regulation of microRNA using promising dietary phytochemicals: Possible preventive and treatment option of malignant mesothelioma.

Biomed Pharmacother. 2017-8-23

[4]
Pterostilbene exerts anticancer activity on non-small-cell lung cancer via activating endoplasmic reticulum stress.

Sci Rep. 2017-8-14

[5]
Anti-inflammatory activity of natural stilbenoids: A review.

Pharmacol Res. 2017-8-9

[6]
The effect of resveratrol, its naturally occurring derivatives and tannic acid on the induction of cell cycle arrest and apoptosis in rat C6 and human T98G glioma cell lines.

Toxicol In Vitro. 2017-9

[7]
Pterostilbene protects against UVB-induced photo-damage through a phosphatidylinositol-3-kinase-dependent Nrf2/ARE pathway in human keratinocytes.

Redox Rep. 2017-5-22

[8]
Pterostilbene prevents AKT-ERK axis-mediated polymerization of surface fibronectin on suspended lung cancer cells independently of apoptosis and suppresses metastasis.

J Hematol Oncol. 2017-3-21

[9]
Pterostilbene Inhibits Human Multiple Myeloma Cells via ERK1/2 and JNK Pathway In Vitro and In Vivo.

Int J Mol Sci. 2016-11-17

[10]
Pterostilbene induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma cells.

Sci Rep. 2016-11-21

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