神经肌肉电刺激疗法对中风后尿失禁患者的疗效：一项随机假对照试验。
Effectiveness of neuromuscular electrical stimulation therapy in patients with urinary incontinence after stroke: A randomized sham controlled trial.
作者信息
Guo Gai-Yan, Kang Yong-Gang
机构信息
Department of Neurology, Yanan University Affiliated Hospital, Yanan.
Department of Neurology, The First People's Hospital of Xianyang City, Xianyang, China.
出版信息
Medicine (Baltimore). 2018 Dec;97(52):e13702. doi: 10.1097/MD.0000000000013702.
BACKGROUND
This study aimed to evaluate the effectiveness of neuromuscular electrical stimulation (NMES) therapy in patients with urinary incontinence after stroke (UIAS).
METHODS
A total of 82 patients with UIAS were randomly assigned to 2 groups that received NMES therapy (NMES group) or sham NMES (sham group) for 10 weeks. The primary efficacy endpoints were measured by urodynamic values, and Overactive Bladder Symptom Score (OABSS). The secondary efficacy endpoints were assessed by International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) score, Barthel Index (BI) scale, and adverse events. All outcomes were evaluated at baseline and at the end of 10 weeks treatment.
RESULTS
After 10-week treatment, the patients received NMES therapy showed better efficacy in primary endpoints of urodynamic values (P <.01) and OABSS (P <.01), and secondary endpoints of ICIQ-SF (P <.01) and BI (P <.01), compared with patients who underwent sham NMES. No adverse events were recorded in both groups.
CONCLUSIONS
In summary, we demonstrated that 10 weeks of NMES therapy was efficacious in patients with UIAS.
背景
本研究旨在评估神经肌肉电刺激（NMES）疗法对中风后尿失禁（UIAS）患者的有效性。
方法
总共82例UIAS患者被随机分为两组，分别接受10周的NMES治疗（NMES组）或假NMES治疗（假手术组）。主要疗效终点通过尿动力学指标和膀胱过度活动症症状评分（OABSS）进行测量。次要疗效终点通过尿失禁咨询问卷简表（ICIQ-SF）评分、巴氏指数（BI）量表和不良事件进行评估。所有结局指标在基线和10周治疗结束时进行评估。
结果
与接受假NMES治疗的患者相比，接受NMES治疗的患者在10周治疗后，尿动力学指标（P<0.01）和OABSS（P<0.01）等主要终点，以及ICIQ-SF（P<0.01）和BI（P<0.01）等次要终点方面显示出更好的疗效。两组均未记录到不良事件。
结论
总之，我们证明了10周的NMES治疗对UIAS患者有效。
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