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一例成人乙型流感及合并感染病例

A Case of Influenza B and Coinfection in an Adult.

作者信息

Shinozaki Taro, Sasahara Kotaro, Iwami Eri, Kuroda Aoi, Matsuzaki Tatsu, Nakajima Takahiro, Terashima Takeshi

机构信息

Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, 5-11-13, Sugano, Ichikawa, Chiba 272-0824, Japan.

出版信息

Case Rep Infect Dis. 2018 Nov 25;2018:3529358. doi: 10.1155/2018/3529358. eCollection 2018.

Abstract

A 19-year-old woman was referred to our hospital because of a persistent fever and cough that lasted for over a week. Influenza B virus infection was diagnosed using the rapid test kit. Initially, the patient was diagnosed with influenza B infection associated with lobar pneumonia and treated with an anti-influenza virus drug and sulbactam/ampicillin. The patient's fever persisted, and her respiratory condition worsened. On day 5, a computed tomography (CT) scan revealed an extension of the consolidation areas in the left lung and new opacities in the right lung. The antibiotic treatment was changed to meropenem and levofloxacin, and the patient's physical condition gradually improved. A sputum sample revealed the presence of -specific DNA. Both influenza B virus and infections were confirmed serologically. This was a case of coinfection with influenza B virus and in a healthy young woman. The pneumonia diagnosis was delayed because the predominant feature observed in the CT scan was dense consolidation. should be considered as one of the causative pathogens in influenza coinfection cases with CT scan images presenting dense consolidation.

摘要

一名19岁女性因持续发热和咳嗽超过一周被转诊至我院。使用快速检测试剂盒诊断为乙型流感病毒感染。最初,患者被诊断为与大叶性肺炎相关的乙型流感感染,并接受了抗流感病毒药物和舒巴坦/氨苄西林治疗。患者发热持续,呼吸状况恶化。第5天,计算机断层扫描(CT)显示左肺实变区域扩大,右肺出现新的混浊。抗生素治疗改为美罗培南和左氧氟沙星,患者身体状况逐渐改善。痰标本检测发现存在特异性DNA。血清学证实同时感染了乙型流感病毒和[未明确病原体名称]。这是一例健康年轻女性同时感染乙型流感病毒和[未明确病原体名称]的病例。由于CT扫描中观察到的主要特征是致密实变,[未明确病原体名称]肺炎的诊断被延迟。在CT扫描图像呈现致密实变的流感合并感染病例中,[未明确病原体名称]应被视为致病病原体之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1894/6286767/b1e15a90386c/CRIID2018-3529358.001.jpg

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