种植微生物组。
Planting the Microbiome.
机构信息
Texas Children's Microbiome Center, Department of Pathology, Texas Children's Hospital, Houston, TX, USA; Department of Pathology & Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, USA. Electronic address: https://twitter.com/@DrJKSpinler.
Children's Nutrition Research Center, Baylor College of Medicine, Houston, TX, USA.
出版信息
Trends Microbiol. 2019 Feb;27(2):90-93. doi: 10.1016/j.tim.2018.12.001. Epub 2018 Dec 29.
Plant-derived microRNAs stabilized by species-specific lipid nanoparticles mediate interkingdom communication through bacterial intermediates and impact consumer health. Ingested by distinct gut bacteria, these microRNA-containing particles alter bacterial gene expression to affect host immunity. This three-kingdom interplay provides compelling approaches for health-directed dietary interventions for consumers.
植物来源的 microRNAs 被物种特异性脂质纳米颗粒稳定，通过细菌中间体介导种间通讯，并影响消费者健康。这些含有 microRNA 的颗粒被不同的肠道细菌摄取，改变细菌基因表达，从而影响宿主免疫。这种三界相互作用为消费者提供了有吸引力的健康导向饮食干预方法。
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