Ojurongbe Olusola, Okorie Patricia Nkem, Opatokun Rofiat Labake, Ojurongbe Taiwo Adetola, Mabayoje Victor Olatunji, Olowe Olugbenga Adekunle, Adeyeba Oluwaseyi Adegboyega
Ladoke Akintola University of Technology, PMB 4400, Osogbo, Nigeria.
Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan.
Afr Health Sci. 2018 Sep;18(3):542-551. doi: 10.4314/ahs.v18i3.11.
and soil transmitted helminth (STHs) infection are widespread in sub-Sahara Africa, where co-infection is also common. This study assessed the prevalence of these infections and their risk factors among pregnant women in Osogbo, Nigeria.
A total of 200 pregnant women attending the antenatal clinic were recruited. was detected using thick and thin film methods, while formol ether concentration method was used for STHs detection. A questionnaire was used to investigate the possible risk factors associated with acquisition of malaria and helminth infections.
The prevalence of , STHs and their co-infection was 29.5%, 12% and 5% respectively. , STHs and + STHs co-infection was significantly higher in primigravidae (52.5% vs 58.3% vs 80%) than in secongravidae (18.6% vs 25.0% vs 20%) and multigravidae (28.8% vs 16.7% vs 0%) (p=0.02). Prevalence associated factors identified for was age (p=0.0001) while gravidity (p=0.02) was identified for + STHs co-infection.
High prevalence of and helminth infections was observed among the pregnant women with primigravidae being the most susceptible to co-infection. There is an urgent need to implement an effective malaria and STHs preventive method for this high risk population.
撒哈拉以南非洲地区土壤传播性蠕虫（STHs）感染广泛，同时合并感染也很常见。本研究评估了尼日利亚奥索博地区孕妇中这些感染的流行情况及其危险因素。
共招募了200名到产前诊所就诊的孕妇。采用厚薄血膜法检测疟疾，采用甲醛乙醚浓缩法检测土壤传播性蠕虫。使用问卷调查与疟疾和蠕虫感染获得相关的可能危险因素。
疟疾、土壤传播性蠕虫及其合并感染的患病率分别为29.5%、12%和5%。初产妇中疟疾、土壤传播性蠕虫以及疟疾+土壤传播性蠕虫合并感染的患病率（分别为52.5%、58.3%和80%）显著高于经产妇（分别为18.6%、25.0%和20%）和多产妇（分别为28.8%、16.7%和0%）（p=0.02）。确定的与疟疾相关的危险因素为年龄（p=0.0001），而与疟疾+土壤传播性蠕虫合并感染相关的危险因素为妊娠次数（p=0.02）。
在孕妇中观察到疟疾和蠕虫感染的高患病率，初产妇最易发生合并感染。迫切需要为这一高危人群实施有效的疟疾和土壤传播性蠕虫预防方法。
