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Prevalence of Cardiovascular Risk Factors and Strokes in Younger Adults.年轻成年人中心血管危险因素及中风的患病率
JAMA Neurol. 2017 Jun 1;74(6):695-703. doi: 10.1001/jamaneurol.2017.0020.
2
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.《2017年心脏病和中风统计数据更新:美国心脏协会报告》
Circulation. 2017 Mar 7;135(10):e146-e603. doi: 10.1161/CIR.0000000000000485. Epub 2017 Jan 25.
3
Hospital Variation in Functional Recovery After Stroke.中风后功能恢复的医院差异。
Circ Cardiovasc Qual Outcomes. 2017 Jan;10(1). doi: 10.1161/CIRCOUTCOMES.115.002391.
4
Mexican Americans are Less Likely to Return to Work Following Stroke: Clinical and Policy Implications.墨西哥裔美国人中风后重返工作岗位的可能性较小:临床及政策意义
J Stroke Cerebrovasc Dis. 2016 Aug;25(8):1851-5. doi: 10.1016/j.jstrokecerebrovasdis.2016.03.015. Epub 2016 Apr 28.
5
Stroke incidence and mortality trends in US communities, 1987 to 2011.美国社区 1987 至 2011 年的中风发病率和死亡率趋势。
JAMA. 2014 Jul 16;312(3):259-68. doi: 10.1001/jama.2014.7692.
6
Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.《卒中和短暂性脑缺血发作患者卒中预防指南:美国心脏协会/美国卒中协会医疗保健专业人员指南》。
Stroke. 2014 Jul;45(7):2160-236. doi: 10.1161/STR.0000000000000024. Epub 2014 May 1.
7
Secondary stroke prevention.二级卒中预防。
Lancet Neurol. 2014 Feb;13(2):178-94. doi: 10.1016/S1474-4422(13)70255-2. Epub 2013 Dec 20.
8
Persistent ischemic stroke disparities despite declining incidence in Mexican Americans.尽管墨西哥裔美国人的缺血性中风发病率下降,但仍存在持续性的发病差异。
Ann Neurol. 2013 Dec;74(6):778-85. doi: 10.1002/ana.23972. Epub 2013 Aug 13.
9
Secondary prevention in patients with vascular disease. A population based study on the underuse of recommended medications.血管疾病患者的二级预防。一项关于推荐药物未被充分使用的基于人群的研究。
J Neurol Neurosurg Psychiatry. 2013 Mar;84(3):348-53. doi: 10.1136/jnnp-2012-303267. Epub 2012 Nov 14.
10
Age at stroke: temporal trends in stroke incidence in a large, biracial population.发病年龄:大型、多种族人群中风发病率的时间趋势。
Neurology. 2012 Oct 23;79(17):1781-7. doi: 10.1212/WNL.0b013e318270401d. Epub 2012 Oct 10.

中年复发中风与没有初级保健医生有关。

Recurrent stroke in midlife is associated with not having a primary care physician.

机构信息

From the Stroke Program (R.J.L., L.D.L., D.B.Z., K.A.K., L.E.S., J.F.B., D.A.L., D.L.B., L.B.M.), Department of Epidemiology (L.D.L., E.C.C., L.B.M.), Department of Biostatistics (B.N.S.), and Department of Internal Medicine (D.A.L.), University of Michigan, Ann Arbor.

出版信息

Neurology. 2019 Feb 5;92(6):e560-e566. doi: 10.1212/WNL.0000000000006878. Epub 2019 Jan 4.

DOI:10.1212/WNL.0000000000006878
PMID:30610095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6382061/
Abstract

OBJECTIVE

To determine using a population-based study whether midlife stroke patients having a primary care physician (PCP) at the time of first stroke have a lower risk of stroke recurrence and mortality than those who do not have a PCP.

METHODS

First-ever ischemic stroke patients 45 to 64 years of age at stroke onset were ascertained through the Brain Attack Surveillance in Corpus Christi (BASIC) project from 2000 to 2013 in Texas. Cox proportional hazards models were used to examine the association between not having a PCP and stroke recurrence or all-cause mortality in separate models. Cases were followed up for up to 5 years or until December 31, 2013, whichever came first. Cases were censored for recurrence if they died before experiencing a recurrent event. We adjusted for clinical risk factors that could be associated with having a PCP and recurrence or mortality.

RESULTS

There were 663 first-occurrence ischemic stroke cases. Of these, 77% had a PCP, 43% were female, and average age was 55.6 years. Five-year recurrence risk was 14.6%, and mortality risk was 19.2%. Not having a PCP was associated with higher recurrence risk (adjusted hazard ratio 1.75, 95% confidence interval 1.02-3.02). Having a PCP was not associated with mortality. Sensitivity analyses showed that results were robust to different ways to adjust for chronic conditions.

CONCLUSION

This study found lower rates of stroke recurrence among those with a PCP at the time of first stroke. Future studies could determine the value of establishing a PCP before stroke hospital discharge for secondary stroke prevention.

摘要

目的

通过一项基于人群的研究,确定中年卒中患者在首次卒中时是否有初级保健医生(PCP)比没有 PCP 的患者卒中复发和死亡风险更低。

方法

2000 年至 2013 年,在德克萨斯州通过脑卒中超监护察项目(BASIC)确定了发病时年龄在 45 至 64 岁的首次缺血性卒中患者。使用 Cox 比例风险模型分别在单独的模型中检查无 PCP 与卒中复发或全因死亡率之间的关联。对病例进行了长达 5 年的随访,或直至 2013 年 12 月 31 日,以先到者为准。如果病例在复发前死亡,则对复发进行删失。我们调整了可能与 PCP 和复发或死亡率相关的临床危险因素。

结果

共有 663 例首发缺血性卒中病例。其中,77%有 PCP,43%为女性,平均年龄为 55.6 岁。5 年复发风险为 14.6%,死亡率风险为 19.2%。没有 PCP 与更高的复发风险相关(调整后的风险比 1.75,95%置信区间 1.02-3.02)。有 PCP 与死亡率无关。敏感性分析表明,结果在不同的慢性疾病调整方式下都是稳健的。

结论

本研究发现,在首次卒中时有 PCP 的患者卒中复发率较低。未来的研究可以确定在卒中出院后建立 PCP 以进行二级卒中预防的价值。