Filho Edilberto Araújo, Fácio Cássio Leão, Machado-Paula Ligiane Alves, Oliveira Mariana Angelozzi de, Martinhago Ciro Dresch, Araújo Leonardo Previato, Araújo Lígia Fernanda P
Center of Human Reproduction of São José do Rio Preto, São José do Rio Preto - SP, Brazil.
Chromosome Genomic Medicine, São Paulo - SP, Brazil.
JBRA Assist Reprod. 2019 Apr 30;23(2):172-174. doi: 10.5935/1518-0557.20180081.
We describe a case of a 37-year-old female, indicated for fertilisation. She developed skin rash on her trunk and limbs, during the treatment. RT-PCR results were positive in her blood and negative in her husband's blood and semen. Oocyte aspiration was performed, retrieving 7 oocytes, follicular fluid, and cumulus cells. RT-PCR results for the follicular fluid and cumulus cells were negative for ZIKV, and positive for only 2 oocytes. This is the first report in the literature analysing ZIKV in the follicular fluid, cumulus cells, and oocytes, and will contribute to the understanding of ZIKV infection and transmission.
我们描述了一例37岁的接受受精治疗的女性病例。在治疗期间，她的躯干和四肢出现了皮疹。逆转录聚合酶链反应（RT-PCR）结果显示她的血液呈阳性，而她丈夫的血液和精液呈阴性。进行了卵母细胞抽吸，获得了7个卵母细胞、卵泡液和卵丘细胞。卵泡液和卵丘细胞的RT-PCR结果显示寨卡病毒（ZIKV）为阴性，仅2个卵母细胞为阳性。这是文献中首篇分析卵泡液、卵丘细胞和卵母细胞中寨卡病毒的报告，将有助于理解寨卡病毒的感染和传播。
