Faculty of Science, Department of Chemistry, Kuwait University, P.O. Box: 5969, 13060, Kuwait City, Kuwait.
Mikrochim Acta. 2019 Jan 7;186(2):55. doi: 10.1007/s00604-018-3118-6.
In this review, an introduction is given to provide the fundamental principles of magnetic droplet microfluidics. This is followed by a thorough discussion of methods that have been developed for the continuous generation of magnetic droplets and their controlled and precise manipulation by using external magnetic fields. Next, attention is given to techniques devised for the continuous fabrication of magnetic materials in droplets with an emphasis on the synthesis and modification of magnetic nanoparticles (MNPs), magnetic microstructures, Janus microparticles and magnetic hydrogels. In addition, selected applications of continuous magnetic droplets in (bio)assays and detection methods are discussed. The review (with 113 refs.) ends with concluding remarks and a discussion of current challenges and the future outlook for the field of continuous magnetic droplet microfluidics. Graphical abstract Continuous generation of magnetic droplets in microfluidic devices has the advantage of producing droplets at high frequencies and therefore has been exploited for the synthesis and generation of magnetic microparticles, manipulation, performing (bio)assyas and detection of magnetic contents.
在这篇综述中，首先介绍了磁滴微流控的基本原理。然后，详细讨论了通过外部磁场连续生成磁滴并对其进行控制和精确操作的方法。接下来，重点介绍了在液滴中连续制备磁性材料的技术，包括磁性纳米粒子（MNPs）、磁性微结构、Janus 微颗粒和磁性水凝胶的合成和修饰。此外，还讨论了连续磁滴在（生物）分析和检测方法中的一些应用。（共 113 篇参考文献）本文以连续磁滴微流控领域的当前挑战和未来展望结束。
图摘要：在微流控装置中连续生成磁滴具有高频产生液滴的优点，因此已被用于磁性微颗粒的合成和生成、操作、（生物）分析物的检测。
