Zanghi Brian M, Gardner Cari L
Nestlé Purina Research, St. Louis, MO, United States.
Front Vet Sci. 2018 Dec 18;5:317. doi: 10.3389/fvets.2018.00317. eCollection 2018.
Water intake and urine measures were evaluated in dogs offered tap water (TW) or a nutrient-enriched water (NW) supplement while fed dry food with TW in a bucket. Baseline (day-7) urine specific gravity (U) was analyzed from healthy, adult small breed dogs ( = 21; 2-11 years). Dogs ( = 16) were selected with ≥1.015 U, then equally divided into 2 groups balanced for U. Groups received either TW or NW in a bowl for 56 days. Dose for each dog was 0.5:1 water-to-calorie ratio (mL:kcal ME/d) from days 1-49 to evaluate sustained intake of a moderate volume, or 2:1 water-to-calorie ratio from days 50-56 to evaluate short-term intake of a large volume, based on baseline food calorie intake. Daily food calorie and total liquid intake (TLI; g/d; sum of NW or TW in a bowl and bucket water) was used to calculate weekly intake. U was measured on days -7, 14, 42, 56. Calorie intake was not different ( > 0.49). A significant ( < 0.001) time-by-treatment interaction resulted for TLI with baseline similar between groups and no difference between weeks for the TW group. Following baseline, NW group had increased ( < 0.05) TLI every week, except for week 2 ( = 0.07). A significant ( < 0.002) time-by-treatment interaction resulted for U, with baseline similar between groups and no difference between sampling days for the TW group (varied by ≤ 0.006 g/mL), whereas NW group was lower ( < 0.01) on days 42 (1.018 g/mL) and 56 (1.014 g/mL) vs. baseline (1.026 g/mL). This study indicates that all dogs offered the NW supplement increased their TLI and produced a more dilute urine, which suggests an improvement in indices associated with chronic hydration.
在给狗喂装在桶里的自来水的同时,评估了饮用自来水(TW)或富含营养的水(NW)补充剂的狗的水摄入量和尿量。从健康的成年小型犬(n = 21;2 - 11岁)中分析基线(第7天)尿比重(U)。选择尿比重≥1.015的狗(n = 16),然后根据尿比重将其平均分为2组。两组狗在碗中分别饮用TW或NW,持续56天。根据基线食物卡路里摄入量,从第1 - 49天,每只狗的剂量为水与卡路里比0.5:1(毫升:千卡代谢能/天),以评估中等量的持续摄入量,或从第50 - 56天为2:1水与卡路里比,以评估大量的短期摄入量。每日食物卡路里和总液体摄入量(TLI;克/天;碗中NW或TW与桶中水的总和)用于计算每周摄入量。在第 - 7、14、42、56天测量尿比重。卡路里摄入量无差异(P > 0.49)。TLI出现显著的(P < 0.001)时间×处理交互作用,两组之间基线相似,TW组各周之间无差异。基线后,除第2周(P = 0.07)外,NW组每周TLI均增加(P < 0.05)。尿比重出现显著的(P < 0.002)时间×处理交互作用,两组之间基线相似,TW组各采样日之间无差异(变化≤0.006克/毫升),而NW组在第42天(1.018克/毫升)和第56天(1.014克/毫升)时尿比重低于基线(1.026克/毫升)(P < 0.01)。本研究表明,所有给予NW补充剂的狗都增加了它们的TLI并产生了更稀释的尿液,这表明与慢性水合作用相关的指标有所改善。