Abdo Nour, Ibraheem Nadia, Obeidat Nail, Graboski-Bauer Ashley, Batieha Anwar, Altamimi Nada, Khatatbih Moawia
Department of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Department of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Epigenet Insights. 2018 Dec 4;11:2516865718813122. doi: 10.1177/2516865718813122. eCollection 2018.
We aim to address public knowledge, attitudes, and practices relative to prenatal genetic testing as a starting point for policy development in Jordan.
We conducted a cross-sectional prenatal genetic testing knowledge, attitudes, and practices survey with 1111 women recruited at obstetrics and gynecology clinics nationwide. Data were analyzed using a variety of descriptive and inferential statistical tests.
The overwhelming majority (>94%) of participants considered prenatal genetic testing, particularly non-invasive prenatal genetic screening, procedures to be good, comfortable, and reasonable, even when the non-diagnostic nature of non-invasive prenatal genetic screening was explained. Likewise, 95% encouraged the implementation of non-invasive prenatal genetic screening within the Jordanian health system, but most preferred it to remain optional. However, women in higher-risk age brackets, in consanguineous marriages, and with less education were significantly less interested in learning about non-invasive prenatal genetic screening. Only 60% of women interviewed were satisfied with the services provided by their obstetric/gynecologist. The more satisfied the women were, the more they are likely to adapt non-invasive prenatal genetic screening.
In sum, although the data support the receptivity of Jordanian women to national implementation of non-invasive prenatal genetic screening, such policies should be accompanied by health education to increase the genetic literacy of the population and to engage high-risk populations. Thus, this offers rare insight into the readiness of 1 particular Arab population to adapt non-invasive prenatal genetic screening technologies.
我们旨在探讨公众关于产前基因检测的知识、态度和行为，以此作为约旦政策制定的起点。
我们对在全国妇产科诊所招募的1111名女性进行了一项关于产前基因检测知识、态度和行为的横断面调查。使用多种描述性和推断性统计测试对数据进行分析。
绝大多数（>94%）参与者认为产前基因检测，尤其是无创产前基因筛查，即使在解释了无创产前基因筛查的非诊断性质后，仍是良好、舒适且合理的程序。同样，95%的人鼓励在约旦医疗系统中实施无创产前基因筛查，但大多数人希望它保持可选项。然而，年龄较大、处于近亲婚姻且受教育程度较低的女性对了解无创产前基因筛查的兴趣明显较低。只有60%接受访谈的女性对她们的妇产科医生提供的服务感到满意。女性越满意，就越有可能接受无创产前基因筛查。
总之，尽管数据表明约旦女性接受在全国实施无创产前基因筛查，但此类政策应辅以健康教育，以提高民众的基因知识水平并吸引高危人群。因此，这为特定阿拉伯人群接受无创产前基因筛查技术的准备情况提供了难得的见解。
