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所选β-内酰胺类抗生素对流感嗜血杆菌的比较活性

Comparative activities of selected beta-lactam antibiotics against Haemophilus influenzae.

作者信息

Jorgensen J H, Alexander G A

出版信息

Antimicrob Agents Chemother. 1978 Feb;13(2):342-3. doi: 10.1128/AAC.13.2.342.

Abstract

The comparative activities of ampicillin, cefamandole, cefoxitin, cefaclor, and cefatrizine against both beta-lactamase-producing and non-beta-lactamase-producing isolates of Haemophilus influenzae were determined by using an agar dilution susceptibility test procedure. Ampicillin was the most active drug tested against non-beta-lactamase-producing isolates, whereas cefamandole was most active against beta-lactamase-producing strains.

摘要

采用琼脂稀释药敏试验方法,测定了氨苄西林、头孢孟多、头孢西丁、头孢克洛和头孢曲嗪对产β-内酰胺酶和不产β-内酰胺酶的流感嗜血杆菌菌株的相对活性。氨苄西林是对不产β-内酰胺酶菌株活性最强的受试药物,而头孢孟多对产β-内酰胺酶菌株活性最强。

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