在脑脊液中快速检测耐氨苄西林流感嗜血杆菌产生的β-内酰胺酶。
Rapid detection in spinal fluid of beta-lactamase produced by ampicillin-resistant Haemophilus influenzae.
作者信息
Boughton W H
出版信息
J Clin Microbiol. 1982 Jun;15(6):1167-8. doi: 10.1128/jcm.15.6.1167-1168.1982.
Abstract
The chromogenic cephalosporin nitrocefin was used to detect the presence of beta-lactamase in cerebrospinal fluid of patients suffering from ampicillin-resistant Haemophilus influenzae meningitis. Five samples of spinal fluid containing ampicillin-resistant isolates were studied, and all had beta-lactamase activity. When samples of spinal fluid containing 33 ampicillin-sensitive isolates and 234 sterile specimens were tested, no beta-lactamase activity was detected.
摘要
用显色头孢菌素硝噻吩来检测患有耐氨苄西林流感嗜血杆菌脑膜炎患者脑脊液中β-内酰胺酶的存在情况。对5份含有耐氨苄西林分离株的脑脊液样本进行了研究，所有样本均有β-内酰胺酶活性。当对含有33株氨苄西林敏感分离株的脑脊液样本和234份无菌标本进行检测时，未检测到β-内酰胺酶活性。
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