骆驼蓬碱在洋葱分生组织细胞中紫外线介导的毒性生物活性。
UV-mediated toxic bioactivity of harmine in the meristematic cells of Allium cepa.
作者信息
Hazen M J, Gutiérrez-Gonzálvez M G
机构信息
Departmento de Biología, Unidad de Citología e Histología, Facultad de Ciencias, Universidad Autónoma de Madrid, Spain.
出版信息
Mutagenesis. 1988 Jul;3(4):333-5. doi: 10.1093/mutage/3.4.333.
PMID:3062322
Abstract
The photodynamic effect of harmine and UV light was studied by measuring the number of sister-chromatid exchanges and micronuclei induced by this treatment in Allium cepa meristematic cells. A significant increase in the frequencies of both cytogenetic events was observed when proliferating cells were treated for 4 h with harmine followed by irradiation with UV light for 3 min.
摘要
通过测量这种处理在洋葱根尖分生组织细胞中诱导的姐妹染色单体交换和微核数量，研究了哈尔明与紫外线的光动力效应。当增殖细胞先用哈尔明处理4小时，然后用紫外线照射3分钟时，观察到这两种细胞遗传学事件的频率均显著增加。
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