Department of Laboratory Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Ann Lab Med. 2019 May;39(3):317-321. doi: 10.3343/alm.2019.39.3.317.
In May 2015, we conducted a voluntary online survey on laboratory diagnostic assays for infection (CDI) across clinical microbiology laboratories in Korea. Responses were obtained from 66 laboratories, including 61 hospitals and five commercial laboratories. Among them, nine laboratories reported having not conducted CDI assays. The toxin AB enzyme immunoassay (toxin AB EIA), nucleic acid amplification test (NAAT), and culture, alone or in combination with other assays, were used in 51 (89.5%), 37 (64.9%), and 37 (64.9%) of the remaining 57 laboratories, respectively, and 23 (40.4%) of the laboratories performed all three assays. Only one laboratory used the glutamate dehydrogenase assay. Nine laboratories used the toxin AB EIA as a stand-alone assay. The median (range) of examined specimens in one month for the toxin AB EIA, NAAT, and culture was 160 (50-2,060), 70 (7-720), and 130 (9-750), respectively. These findings serve as valuable basic data regarding the current status of laboratory diagnosis of CDI in Korea, offering guidance for improved implementation.
2015 年 5 月，我们对韩国临床微生物学实验室的 感染（CDI）实验室诊断检测方法进行了一项自愿性在线调查。共有 66 家实验室做出回应，其中包括 61 家医院和 5 家商业实验室。其中 9 家实验室报告未进行 CDI 检测。毒素 AB 酶联免疫吸附试验（toxin AB EIA）、核酸扩增试验（NAAT）和 培养，单独或组合使用，分别在 51 家（89.5%）、37 家（64.9%）和 37 家（64.9%）剩余的 57 家实验室中使用，23 家（40.4%）实验室进行了所有三种检测。只有一家实验室使用谷氨酸脱氢酶检测法。9 家实验室将毒素 AB EIA 作为独立检测法使用。毒素 AB EIA、NAAT 和 培养在一个月内检测的样本中位数（范围）分别为 160（50-2060）、70（7-720）和 130（9-750）。这些发现为了解韩国 CDI 实验室诊断的现状提供了有价值的基础数据，为改进实施提供了指导。
