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老年髋部骨折患者围手术期营养补充与骨骼肌质量。

Perioperative nutritional supplementation and skeletal muscle mass in older hip-fracture patients.

机构信息

Department of Surgery, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

Department of Human Biology, NUTRIM School for Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, Maastricht, The Netherlands.

出版信息

Nutr Rev. 2019 Apr 1;77(4):254-266. doi: 10.1093/nutrit/nuy055.

DOI:10.1093/nutrit/nuy055
PMID:30624706
Abstract

Older people with hip fractures are often malnourished at the time of fracture, which can have substantial influence on mortality and clinical outcomes, as well as functional outcome and quality of life. A close relationship between protein intake and muscle maintenance has been demonstrated. Skeletal muscle weakness is an independent risk factor for falls and fall-related injuries in the elderly and is an independent marker of prognosis. However, the effect of perioperative nutritional interventions on outcomes in elderly hip-fracture patients remains controversial. In this narrative review, an overview is presented of the existing literature on nutritional status and sarcopenia in elderly hip-fracture patients, clinical outcomes, and the effects of nutritional intervention on outcome and rehabilitation in this patient group.

摘要

老年人髋部骨折时常常伴有营养不良,这对死亡率和临床结果,以及功能结果和生活质量有重大影响。已经证明蛋白质摄入与肌肉维持之间存在密切关系。骨骼肌无力是老年人跌倒和跌倒相关损伤的独立危险因素,也是预后的独立标志物。然而,围手术期营养干预对老年髋部骨折患者结局的影响仍存在争议。在本综述中,对老年髋部骨折患者的营养状况和肌肉减少症、临床结局以及营养干预对该患者群体的结局和康复影响的现有文献进行了概述。

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