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采用光学相干断层扫描进行评估的剥脱性铒激光与微针射频治疗萎缩性痤疮瘢痕的半脸对照研究。

Split-face comparative study of fractional Er:YAG laser versus microneedling radiofrequency in treatment of atrophic acne scars, using optical coherence tomography for assessment.

作者信息

Emam Amira A M, Nada Hesham A, Atwa Mona A, Tawfik Noha Z

机构信息

Department of Dermatology and Venereology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.

出版信息

J Cosmet Dermatol. 2022 Jan;21(1):227-236. doi: 10.1111/jocd.14071. Epub 2021 Mar 21.

Abstract

BACKGROUND

Efficacy and safety of ablative fractional laser used for treatment of acne scars have been described in several studies. Recently, microneedling radiofrequency treatment has been showing promising results with low risk of side effects and rapid healing time.

OBJECTIVE

To study efficacy and safety of ablative fractional Er:YAG laser 2940 nm and microneedling radiofrequency for facial atrophic acne scar.

METHODS

21 patients with atrophic postacne scars were randomized to MRF for one half of the face and laser for the other half. Four sessions were performed monthly. For evaluation, the validated scale "Quantitative Global Grading System for Postacne Scarring" and patient's satisfaction were used before and 3 months after treatment. Optical coherence tomography imaging of the skin was used as an objective tool for assessment.

RESULTS

Both sides showed significant improvement on clinical evaluation with no significant difference. Optical coherence tomography assessment showed significant increase of both epidermal and dermal thickness compared to baseline.

CONCLUSION

Both MRF and ablative fractional Er. YAG laser 2940 nm are effective in the treatment of post acne scars. Microneedling radiofrequency is better tolerated, with lower downtime and fewer side effects.

摘要

背景

多项研究已描述了剥脱性点阵激光用于治疗痤疮瘢痕的疗效和安全性。最近,微针射频治疗已显示出有前景的结果,副作用风险低且愈合时间快。

目的

研究2940nm剥脱性点阵铒激光和微针射频治疗面部萎缩性痤疮瘢痕的疗效和安全性。

方法

21例萎缩性痤疮后瘢痕患者被随机分为一半面部接受微针射频治疗,另一半面部接受激光治疗。每月进行4次治疗。为进行评估,在治疗前和治疗后3个月使用经过验证的“痤疮瘢痕定量整体分级系统”量表和患者满意度。皮肤光学相干断层扫描成像用作评估的客观工具。

结果

临床评估显示两侧均有显著改善,无显著差异。光学相干断层扫描评估显示与基线相比,表皮和真皮厚度均显著增加。

结论

微针射频和2940nm剥脱性点阵铒激光在治疗痤疮后瘢痕方面均有效。微针射频耐受性更好,停工期更短,副作用更少。

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