Department of Respiratory Medicine, Nottingham City Hospital, Nottingham, UK.
Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.
Thorax. 2019 Jul;74(7):705-706. doi: 10.1136/thoraxjnl-2018-212723. Epub 2019 Jan 10.
Asthma exacerbations are a common reason for hospital admission. We sought to identify whether patterns of inhaler prescribing are significantly associated with regional asthma admission rates. Asthma admission rates were obtained for English Clinical Commissioning Group (CCG) regions from 2013/2014 to 2016/2017. Raw prescribing data were obtained from OpenPrescribing.net, based on monthly general practice-level data published by the National Health Service Business Services Authority. Data were analysed using a linear mixed effects model. The ratio of salbutamol to inhaled corticosteroid prescriptions within a CCG was positively associated with asthma admission rates, independently of median age, asthma prevalence and socioeconomic deprivation.
哮喘恶化是住院的常见原因。我们试图确定吸入器处方模式是否与区域哮喘入院率有显著关联。从 2013/2014 年到 2016/2017 年,我们获得了英国临床委托组(CCG)区域的哮喘入院率。原始处方数据来自 OpenPrescribing.net,基于国家卫生服务商业服务局发布的每月全科实践水平数据。使用线性混合效应模型进行数据分析。CCG 内沙丁胺醇与吸入皮质类固醇的处方比例与哮喘入院率呈正相关,与中位年龄、哮喘流行率和社会经济剥夺无关。