Shelley M, Croft P, Chapman S, Pantin C
Industrial and Community Health Research Centre, School of Postgraduate Medicine, Keele University, North Staffordshire Medical Institute, Stoke on Trent.
BMJ. 1996 Nov 2;313(7065):1124-6. doi: 10.1136/bmj.313.7065.1124.
To investigate the ratio of inhaled corticosteroid to bronchodilator as a measure of the quality of asthma prescribing by general practitioners.
Ecological cross sectional study linking general practitioner asthma prescribing with hospital admission data and a measure of deprivation.
11 family health services authorities in the West Midlands region and 99 general practices in North Staffordshire.
Hospital admission rates for asthma; the ratio of inhaled corticosteroid to bronchodilator; and Townsend deprivation scores.
No overall significant correlation was found between admission rates for asthma and corticosteroid:bronchodilator ratios for family health services authorities (Spearman's rs = -0.109, P = 0.750) or general practices (rs = -0.084, P = 0.407). In deprived family health services authority areas and general practices an inverse non-significant correlation existed between admission rates for asthma and corticosteroid:bronchodilator ratios (rs = -0.300, P = 0.624; rs = -0.218, P = 0.136). In contrast, in more affluent areas and general practices a positive non-significant correlation existed between admission rates and corticosteroid:bronchodilator ratios (rs = 0.371, P = 0.468; rs = 0.038, P = 0.792).
Although the corticosteroid:bronchodilator ratio may be a valid indicator of the quality of prescribing for individual patients with asthma, caution should be applied in interpreting aggregated ratios. Differences in the severity of asthma or the prevalence of chronic obstructive pulmonary disease may explain inconsistent associations between admission rates for asthma and corticosteroid:bronchodilator ratios in family health services authorities and general practices with different deprivation scores.
研究吸入性糖皮质激素与支气管扩张剂的使用比例,以此作为全科医生哮喘处方质量的一项衡量指标。
一项生态横断面研究,将全科医生的哮喘处方与医院入院数据及一项贫困程度衡量指标相联系。
西米德兰兹地区的11个家庭健康服务机构以及北斯塔福德郡的99家全科诊所。
哮喘的住院率;吸入性糖皮质激素与支气管扩张剂的使用比例;以及汤森贫困得分。
对于家庭健康服务机构(斯皮尔曼等级相关系数rs = -0.109,P = 0.750)或全科诊所(rs = -0.084,P = 0.407)而言,哮喘住院率与糖皮质激素:支气管扩张剂使用比例之间未发现总体显著相关性。在贫困的家庭健康服务机构区域及全科诊所中,哮喘住院率与糖皮质激素:支气管扩张剂使用比例之间存在非显著的负相关(rs = -0.300,P = 0.624;rs = -0.218,P = 0.136)。相比之下,在较富裕的地区及全科诊所中,住院率与糖皮质激素:支气管扩张剂使用比例之间存在非显著的正相关(rs = 0.371,P = 0.468;rs = 0.038,P = 0.792)。
虽然糖皮质激素:支气管扩张剂使用比例可能是个体哮喘患者处方质量的有效指标,但在解释汇总比例时应谨慎。哮喘严重程度或慢性阻塞性肺疾病患病率的差异,可能解释了不同贫困得分的家庭健康服务机构及全科诊所中,哮喘住院率与糖皮质激素:支气管扩张剂使用比例之间不一致的关联。