1999 年至 2020 年期间英格兰和威尔士因慢性阻塞性肺疾病和哮喘导致的住院和处方趋势：一项生态学研究。

Trends in hospital admissions and prescribing due to chronic obstructive pulmonary disease and asthma in England and Wales between 1999 and 2020: an ecological study.

机构信息

Faculty of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia.

Al-Noor Specialist Hospital, Mecca, Saudi Arabia.

出版信息

BMC Pulm Med. 2023 Feb 2;23(1):49. doi: 10.1186/s12890-023-02342-6.

OBJECTIVE

To investigate the trends in hospital admissions and medication prescriptions related to asthma and chronic obstructive pulmonary disease (COPD) in England and Wales.

METHODS

An ecological study was conducted between April 1999 and April 2020 using data extracted from the hospital episode statistics database in England and the patient episode database for Wales. The Office of National Statistics mid-year population estimates for 1999 through 2020 were collected, and medication prescription data for 2004-2020 were extracted from the prescription cost analysis database.

RESULTS

The total annual number of COPD and asthma hospital admissions for various causes increased by 82.2%, from 210,525 in 1999 to 383,652 in 2020, representing a 59.1% increase in hospital admission rate (from 403.77 in 1999 to 642.42 per 100,000 persons in 2020, p < 0.05). Chronic obstructive pulmonary disease with acute lower respiratory infection accounted for 38.7% of hospital admissions. Around 34.7% of all hospital admissions involved patients aged 75 and older. Around 53.8% of all COPD and asthma hospital admissions were attributable to females. The annual number of prescriptions dispensed for COPD and asthma medications increased by 42.2%.

CONCLUSIONS

Throughout the study period, hospital admissions due to chronic obstructive pulmonary disease and asthma, as well as medication prescriptions, increased dramatically among all age groups. Hospitalization rates were higher for women. Further observational and epidemiological research is required to identify the factors contributing to increased hospitalization rates.

目的

调查英格兰和威尔士与哮喘和慢性阻塞性肺疾病（COPD）相关的住院和用药情况的趋势。

方法

采用生态研究方法，于 1999 年 4 月至 2020 年 4 月期间，从英格兰的医院入院统计数据库和威尔士的患者入院数据库中提取数据。收集了 1999 年至 2020 年的英国国家统计局年中人口估计数据，并从处方费用分析数据库中提取了 2004 年至 2020 年的药物处方数据。

结果

各种原因导致的 COPD 和哮喘的年住院总人数增加了 82.2%，从 1999 年的 210525 例增至 2020 年的 383652 例，住院率上升了 59.1%（从 1999 年的每 10 万人 403.77 例增至 2020 年的 642.42 例，p<0.05）。慢性阻塞性肺疾病伴急性下呼吸道感染占住院人数的 38.7%。约 34.7%的住院患者年龄在 75 岁及以上。所有 COPD 和哮喘住院患者中，约 53.8%为女性。COPD 和哮喘药物的年处方量增加了 42.2%。