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从摩洛哥马铃薯根际分离出的新诺丝菌素产生菌株链霉菌属Z26的基因组序列草图

Draft Genome Sequence of the Novonestmycin-Producing Strain Streptomyces sp. Z26, Isolated from Potato Rhizosphere in Morocco.

作者信息

Buchmann Anina, Cano-Prieto Carolina, Nafis Ahmed, Barakate Mustapha, Baz Mohamed, Hassani Lahcen, Ortlieb Nico, Niedermeyer Timo H J, Gross Harald

机构信息

Department of Pharmaceutical Biology, Pharmaceutical Institute, University of Tübingen, Tübingen, Germany.

German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.

出版信息

Microbiol Resour Announc. 2019 Jan 3;8(1). doi: 10.1128/MRA.01514-18. eCollection 2019 Jan.

DOI:10.1128/MRA.01514-18
PMID:30637404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6318375/
Abstract

Streptomyces sp. strain Z26 exhibited antifungal activity and turned out to be a producer of the secondary metabolites novonestmycin A and B. The 6.5-Mb draft genome gives insight into the complete secondary metabolite production capacity and builds the basis to find and locate the biosynthetic gene cluster encoding the novonestmycins.

摘要

链霉菌属菌株Z26表现出抗真菌活性，结果证明是次级代谢产物新巢霉素A和B的生产者。650 kb的草图基因组有助于深入了解完整的次级代谢产物生产能力，并为寻找和定位编码新巢霉素的生物合成基因簇奠定基础。