Center for Muscle Biology.
Department of Rehabilitation Sciences, and.
Exerc Sport Sci Rev. 2019 Apr;47(2):108-115. doi: 10.1249/JES.0000000000000181.
Skeletal muscle fiber branching and splitting typically is associated with damage and regeneration and is considered pathological when observed during loading-induced hypertrophy. We hypothesize that fiber splitting is a nonpathological component of extreme loading and hypertrophy, which is primarily supported by evidence in animals, and propose that the mechanisms and consequences of fiber splitting deserve further exploration.
骨骼肌纤维分支和分裂通常与损伤和再生有关,在负荷诱导的肥大过程中观察到这种现象时被认为是病理性的。我们假设纤维分裂是极端负荷和肥大的一种非病理性组成部分,这主要得到了动物研究证据的支持,并提出纤维分裂的机制和后果值得进一步研究。