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髋部骨折的全髋关节置换术:手术时机与手术翻修、失败及死亡率的关系

Total Hip Arthroplasty for Hip Fractures: Time to Surgery With Respect to Surgical Revision, Failure, and Mortality.

作者信息

Müller Franz, Galler Michael, Zellner Michael, Bäuml Christian, Grechenig Stephan, Kottmann Tanja, Füchtmeier Bernd

机构信息

Clinic for Trauma, Orthopaedic and Sports Medicine, Hospital Barmherzige Brüder, Regensburg, Germany.

Medical Statistics, Hamm, Germany.

出版信息

Geriatr Orthop Surg Rehabil. 2019 Jan 4;10:2151459318818162. doi: 10.1177/2151459318818162. eCollection 2019.

Abstract

INTRODUCTION

There are increasing demands to perform surgery of hip fractures without delay. However, few studies have assessed the time to surgery in relation to outcome measurements.

METHODS

A total of 643 consecutive patients with a minimum age of 60 years underwent total hip arthroplasty (THA) for an intracapsular hip fracture. For this retrospective case series, demographic data and the outcome measurements-(1) any surgical revision, (2) implant failure, and (3) mortality-were documented from a prospective clinical database. The time from admission to surgery was also documented prospectively and then data were divided into 4 groups according to the time of surgery: (1) within 12 hours, (2) >12 to 24 hours, (3) >24 to 48 hours, and (4) later than >48 hours. The study end point was 2 years after surgery. Final evaluation was conducted for any missing data through a telephone interview.

RESULTS

The patients comprised 456 women (70.9%) and 187 men (29.1%) with a mean age of 80.2 years (range 60-104 years; standard deviation ±7.4). Descriptive data were without effect in all 4 groups. Time to surgery did not significantly influence revision for any reason ( = .323), implant failure ( = .521), and mortality ( = .643). Cox regression analysis identified male sex ( < .001; 95% confidence interval (CI), 1.27-2.44), American Society of Anesthesiologists score ≥3 ( < .001; 95% CI, 2.12-21.59), C-reactive protein level >21 mg/L ( < .018; 95% CI, 1.09-2.60), hemoglobin level <12.0 g/dL ( = .033; 95% CI, 1.04-2.68), and dementia ( < .000; 95% CI, 1.50-2.86) as independent significant risk factors for mortality.

CONCLUSION

Time to surgery had no effect on revision for any reason, implant failure, and mortality in patients undergoing THA for an intracapsular hip fracture.

摘要

引言

对于髋部骨折手术,人们越来越要求不延迟进行。然而,很少有研究评估手术时间与预后指标之间的关系。

方法

共有643例年龄最小为60岁的连续患者因囊内髋部骨折接受了全髋关节置换术(THA)。对于这个回顾性病例系列,从一个前瞻性临床数据库中记录了人口统计学数据和预后指标——(1)任何手术翻修,(2)植入物失败,以及(3)死亡率。从入院到手术的时间也进行了前瞻性记录,然后根据手术时间将数据分为4组:(1)12小时内,(2)>12至24小时,(3)>24至48小时,以及(4)>48小时后。研究终点为术后2年。通过电话访谈对任何缺失数据进行了最终评估。

结果

患者包括456名女性(70.9%)和187名男性(29.1%),平均年龄为80.2岁(范围60 - 104岁;标准差±7.4)。所有4组的描述性数据均无影响。手术时间对因任何原因进行的翻修(P = 0.323)、植入物失败(P = 0.521)和死亡率(P = 0.643)均无显著影响。Cox回归分析确定男性(P < 0.001;95%置信区间(CI),1.27 - 2.44)、美国麻醉医师协会评分≥3(P < 0.001;95% CI,2.12 - 21.59)、C反应蛋白水平>21 mg/L(P < 0.018;95% CI,1.09 - 2.60)、血红蛋白水平<12.0 g/dL(P = 0.033;95% CI,1.04 - 2.68)以及痴呆(P < 0.000;95% CI,1.50 - 2.86)是死亡率的独立显著危险因素。

结论

对于因囊内髋部骨折接受THA的患者,手术时间对因任何原因进行的翻修、植入物失败和死亡率均无影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adee/6322097/404158c2536d/10.1177_2151459318818162-fig1.jpg

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