托槽识别染料的细胞毒性。
Cytotoxicity of bracket identification dyes.
出版信息
Angle Orthod. 2019 May;89(3):426-431. doi: 10.2319/061218-439.1. Epub 2018 Dec 28.
OBJECTIVES
To investigate the potential cytotoxicity of the bracket identification dyes commonly used in orthodontic fixed appliances.
MATERIALS AND METHODS
Six bracket brands representing the market in various aspects were selected. Ten sets of each bracket brand were acquired, and the identification dyes on them were scraped. They were tested for cytotoxicity at three different levels of concentration (2.5 mg/mL, 5 mg/mL, and 10 mg/mL), with the aid of a real-time cell analysis system. The results were compared within and between the groups. One-way analysis of variance and Tukey's post hoc test were used for statistical analysis.
RESULTS
None of the six investigated dyes displayed cytotoxicity at the 2.5 mg/mL concentration. Of the investigated brands, three at 5 mg/mL and four at 10 mg/mL displayed cytotoxicity.
CONCLUSIONS
Some of the identification dyes in this study did display cytotoxicity at the higher concentrations tested. Alternative methods for bracket identification should be considered.
目的
研究正畸固定矫治器中常用的托槽标识染料的潜在细胞毒性。
材料和方法
选择了代表市场各个方面的六个托槽品牌。每种托槽品牌均获取十套，刮除其上的标识染料。利用实时细胞分析系统，在三个不同浓度水平（2.5 mg/mL、5 mg/mL 和 10 mg/mL）下测试其细胞毒性，并对组内和组间进行比较。采用单因素方差分析和 Tukey 事后检验进行统计学分析。
结果
在所研究的六种染料中，没有一种在 2.5 mg/mL 浓度下显示出细胞毒性。在所研究的品牌中，有三种在 5 mg/mL 浓度下，四种在 10 mg/mL 浓度下显示出细胞毒性。
结论
本研究中的一些标识染料在测试的较高浓度下确实显示出细胞毒性。应考虑使用替代的托槽标识方法。
Zotero 插件